Potentiation of Phase Variation in Multiple Outer-Membrane Proteins During Spread of the Hyperinvasive Neisseria meningitidis Serogroup W ST-11 Lineage

Abstract Background Since 2009, increases in the incidence of invasive meningococcal disease have occurred in the United Kingdom due to a sublineage of the Neisseria meningitidis serogroup W ST-11 clonal complex (hereafter, the “original UK strain”). In 2013, a descendent substrain (hereafter, the “...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of infectious diseases 2019-08, Vol.220 (7), p.1109-1117
Hauptverfasser:	Green, Luke R., Dave, Neelam, Adewoye, Adeolu B., Lucidarme, Jay, Clark, Stephen A., Oldfield, Neil J., Turner, David P. J., Borrow, Ray, Bayliss, Christopher D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesins, Bacterial - genetics BACTERIA Bacterial Outer Membrane Proteins - genetics Bioinformatics Disease transmission DNA, Bacterial - analysis Fimbriae Proteins - genetics Gene expression Gene Expression Regulation, Bacterial Genetic Variation Genomes Genomics Immune response Immunoblotting Invasive meningococcal disease Major and Brief Reports Membrane proteins Meningococcal disease Meningococcal Infections - epidemiology Meningococcal Infections - microbiology Microsatellite Repeats - genetics Molecular Epidemiology Neisseria meningitidis Neisseria meningitidis - genetics Nucleotide sequence Phase variations PilC gene Polymerase chain reaction Porins - genetics Sequence Analysis, DNA Serogroup United Kingdom Whole Genome Sequencing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!