The prevalence and pregnancy outcomes of intrahepatic cholestasis of pregnancy: A retrospective clinical audit review
Background To determine the prevalence and outcomes of intrahepatic cholestasis of pregnancy. Methods A review comparing intrahepatic cholestasis of pregnancy pregnancies to all other pregnancies in three tertiary care Australian hospitals over a 36-month period. Results There were 43,876 pregnancie...
Gespeichert in:
| Veröffentlicht in: | Obstetric medicine 2019-09, Vol.12 (3), p.123-128 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 128 |
|---|---|
| container_issue | 3 |
| container_start_page | 123 |
| container_title | Obstetric medicine |
| container_volume | 12 |
| creator | Gardiner, Fergus W McCuaig, Ruth Arthur, Chris Carins, Thomas Morton, Adam Laurie, Josephine Neeman, Teresa Lim, Boon Peek, Michael J |
| description | Background
To determine the prevalence and outcomes of intrahepatic cholestasis of pregnancy.
Methods
A review comparing intrahepatic cholestasis of pregnancy pregnancies to all other pregnancies in three tertiary care Australian hospitals over a 36-month period.
Results
There were 43,876 pregnancies. The prevalence of intrahepatic cholestasis of pregnancies (n = 319) was 0.7%. There were differences between intrahepatic cholestasis of pregnancy and non-intrahepatic cholestasis of pregnancy mothers including higher prevalence of South Asian (22.6% versus 3.1%, p |
| doi_str_mv | 10.1177/1753495X18797749 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6734627</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_1753495X18797749</sage_id><sourcerecordid>2299460860</sourcerecordid><originalsourceid>FETCH-LOGICAL-c509t-7a6d1dac74ce6193553ea671f014ccfcbd1b8b2626585769925add3574b348a73</originalsourceid><addsrcrecordid>eNp1kUtv1DAUhS0EoqWwZ4UssWET8NsxC6Sq4iVVYlOk7qwb52bGVcYOcTJV_z0JUwaoxMqP891zfXwJecnZW86tfcetlsrpa15bZ61yj8jpelUpZ-rHx72-PiHPSrlhzGgp5FNyIrkWUpj6lMxXW6TDiHvoMQWkkNr1uEmQwh3N8xTyDgvNHY1pGmGLA0wx0LDNPZYJSvylHSve03M64jTmMmCY4h5p6GOKAXoKcxunRdxHvH1OnnTQF3xxv56R758-Xl18qS6_ff56cX5ZBc3cVFkwLW8hWBXQcCe1lgjG8o5xFUIXmpY3dSOMMLrW1jgnNLSt1FY1UtVg5Rn5cPAd5maHbcA1Q--HMe5gvPMZov9XSXHrN3nvjZXKiNXgzb3BmH_MS2K_iyVg30PCPBcvhGNOK2frBX39AL3J85iWeCvllGG1YQvFDlRY_qiM2B0fw5lfZ-ofznQpefV3iGPB7yEuQHUACmzwT9f_Gv4EJdSsbQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2299460860</pqid></control><display><type>article</type><title>The prevalence and pregnancy outcomes of intrahepatic cholestasis of pregnancy: A retrospective clinical audit review</title><source>Access via SAGE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Gardiner, Fergus W ; McCuaig, Ruth ; Arthur, Chris ; Carins, Thomas ; Morton, Adam ; Laurie, Josephine ; Neeman, Teresa ; Lim, Boon ; Peek, Michael J</creator><creatorcontrib>Gardiner, Fergus W ; McCuaig, Ruth ; Arthur, Chris ; Carins, Thomas ; Morton, Adam ; Laurie, Josephine ; Neeman, Teresa ; Lim, Boon ; Peek, Michael J</creatorcontrib><description><![CDATA[Background
To determine the prevalence and outcomes of intrahepatic cholestasis of pregnancy.
Methods
A review comparing intrahepatic cholestasis of pregnancy pregnancies to all other pregnancies in three tertiary care Australian hospitals over a 36-month period.
Results
There were 43,876 pregnancies. The prevalence of intrahepatic cholestasis of pregnancies (n = 319) was 0.7%. There were differences between intrahepatic cholestasis of pregnancy and non-intrahepatic cholestasis of pregnancy mothers including higher prevalence of South Asian (22.6% versus 3.1%, p < 0.001), Indigenous Australian (3.8% versus 1.8%, p < 0.05), and Asian ethnicity (8.4% versus 5.7%, p < 0.05), mothers with a body mass index >35 kg/m2 (10.6% versus 5.5%, p < 0.001), those with diabetes mellitus (25.7% versus 9.8%, p < 0.001), and those with twin births (8.7% versus 2.2%, p < 0.001). The primary clinical outcomes of intrahepatic cholestasis of pregnancy included a median gestational age at delivery of 36.4 (SE 0.09) weeks compared to 38.6 (SE 0.01) weeks (p < 0.001), a lower birth weight (3.12 (SE 0.03) versus 3.31 kg (SE 0.03), p < 0.001), and an increase in special care nursery admissions (44.5% versus 15.3%, p < 0.001).
Conclusion
Treated intrahepatic cholestasis of pregnancy in the population described here had similar mortality outcomes although increased special care nursery admission as compared to the general population.]]></description><identifier>ISSN: 1753-495X</identifier><identifier>EISSN: 1753-4968</identifier><identifier>DOI: 10.1177/1753495X18797749</identifier><identifier>PMID: 31523268</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Diagnostic tests ; Gallbladder diseases ; Liver ; Original ; Pregnancy ; Pregnancy complications</subject><ispartof>Obstetric medicine, 2019-09, Vol.12 (3), p.123-128</ispartof><rights>The Author(s) 2018</rights><rights>The Author(s) 2018 2018 SAGE Publications</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c509t-7a6d1dac74ce6193553ea671f014ccfcbd1b8b2626585769925add3574b348a73</citedby><cites>FETCH-LOGICAL-c509t-7a6d1dac74ce6193553ea671f014ccfcbd1b8b2626585769925add3574b348a73</cites><orcidid>0000-0001-7592-832X ; 0000-0001-9887-714X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734627/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734627/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,21819,27924,27925,43621,43622,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31523268$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gardiner, Fergus W</creatorcontrib><creatorcontrib>McCuaig, Ruth</creatorcontrib><creatorcontrib>Arthur, Chris</creatorcontrib><creatorcontrib>Carins, Thomas</creatorcontrib><creatorcontrib>Morton, Adam</creatorcontrib><creatorcontrib>Laurie, Josephine</creatorcontrib><creatorcontrib>Neeman, Teresa</creatorcontrib><creatorcontrib>Lim, Boon</creatorcontrib><creatorcontrib>Peek, Michael J</creatorcontrib><title>The prevalence and pregnancy outcomes of intrahepatic cholestasis of pregnancy: A retrospective clinical audit review</title><title>Obstetric medicine</title><addtitle>Obstet Med</addtitle><description><![CDATA[Background
To determine the prevalence and outcomes of intrahepatic cholestasis of pregnancy.
Methods
A review comparing intrahepatic cholestasis of pregnancy pregnancies to all other pregnancies in three tertiary care Australian hospitals over a 36-month period.
Results
There were 43,876 pregnancies. The prevalence of intrahepatic cholestasis of pregnancies (n = 319) was 0.7%. There were differences between intrahepatic cholestasis of pregnancy and non-intrahepatic cholestasis of pregnancy mothers including higher prevalence of South Asian (22.6% versus 3.1%, p < 0.001), Indigenous Australian (3.8% versus 1.8%, p < 0.05), and Asian ethnicity (8.4% versus 5.7%, p < 0.05), mothers with a body mass index >35 kg/m2 (10.6% versus 5.5%, p < 0.001), those with diabetes mellitus (25.7% versus 9.8%, p < 0.001), and those with twin births (8.7% versus 2.2%, p < 0.001). The primary clinical outcomes of intrahepatic cholestasis of pregnancy included a median gestational age at delivery of 36.4 (SE 0.09) weeks compared to 38.6 (SE 0.01) weeks (p < 0.001), a lower birth weight (3.12 (SE 0.03) versus 3.31 kg (SE 0.03), p < 0.001), and an increase in special care nursery admissions (44.5% versus 15.3%, p < 0.001).
Conclusion
Treated intrahepatic cholestasis of pregnancy in the population described here had similar mortality outcomes although increased special care nursery admission as compared to the general population.]]></description><subject>Diagnostic tests</subject><subject>Gallbladder diseases</subject><subject>Liver</subject><subject>Original</subject><subject>Pregnancy</subject><subject>Pregnancy complications</subject><issn>1753-495X</issn><issn>1753-4968</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp1kUtv1DAUhS0EoqWwZ4UssWET8NsxC6Sq4iVVYlOk7qwb52bGVcYOcTJV_z0JUwaoxMqP891zfXwJecnZW86tfcetlsrpa15bZ61yj8jpelUpZ-rHx72-PiHPSrlhzGgp5FNyIrkWUpj6lMxXW6TDiHvoMQWkkNr1uEmQwh3N8xTyDgvNHY1pGmGLA0wx0LDNPZYJSvylHSve03M64jTmMmCY4h5p6GOKAXoKcxunRdxHvH1OnnTQF3xxv56R758-Xl18qS6_ff56cX5ZBc3cVFkwLW8hWBXQcCe1lgjG8o5xFUIXmpY3dSOMMLrW1jgnNLSt1FY1UtVg5Rn5cPAd5maHbcA1Q--HMe5gvPMZov9XSXHrN3nvjZXKiNXgzb3BmH_MS2K_iyVg30PCPBcvhGNOK2frBX39AL3J85iWeCvllGG1YQvFDlRY_qiM2B0fw5lfZ-ofznQpefV3iGPB7yEuQHUACmzwT9f_Gv4EJdSsbQ</recordid><startdate>20190901</startdate><enddate>20190901</enddate><creator>Gardiner, Fergus W</creator><creator>McCuaig, Ruth</creator><creator>Arthur, Chris</creator><creator>Carins, Thomas</creator><creator>Morton, Adam</creator><creator>Laurie, Josephine</creator><creator>Neeman, Teresa</creator><creator>Lim, Boon</creator><creator>Peek, Michael J</creator><general>SAGE Publications</general><general>SAGE PUBLICATIONS, INC</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope><scope>K9.</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-7592-832X</orcidid><orcidid>https://orcid.org/0000-0001-9887-714X</orcidid></search><sort><creationdate>20190901</creationdate><title>The prevalence and pregnancy outcomes of intrahepatic cholestasis of pregnancy: A retrospective clinical audit review</title><author>Gardiner, Fergus W ; McCuaig, Ruth ; Arthur, Chris ; Carins, Thomas ; Morton, Adam ; Laurie, Josephine ; Neeman, Teresa ; Lim, Boon ; Peek, Michael J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c509t-7a6d1dac74ce6193553ea671f014ccfcbd1b8b2626585769925add3574b348a73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Diagnostic tests</topic><topic>Gallbladder diseases</topic><topic>Liver</topic><topic>Original</topic><topic>Pregnancy</topic><topic>Pregnancy complications</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gardiner, Fergus W</creatorcontrib><creatorcontrib>McCuaig, Ruth</creatorcontrib><creatorcontrib>Arthur, Chris</creatorcontrib><creatorcontrib>Carins, Thomas</creatorcontrib><creatorcontrib>Morton, Adam</creatorcontrib><creatorcontrib>Laurie, Josephine</creatorcontrib><creatorcontrib>Neeman, Teresa</creatorcontrib><creatorcontrib>Lim, Boon</creatorcontrib><creatorcontrib>Peek, Michael J</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Obstetric medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gardiner, Fergus W</au><au>McCuaig, Ruth</au><au>Arthur, Chris</au><au>Carins, Thomas</au><au>Morton, Adam</au><au>Laurie, Josephine</au><au>Neeman, Teresa</au><au>Lim, Boon</au><au>Peek, Michael J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The prevalence and pregnancy outcomes of intrahepatic cholestasis of pregnancy: A retrospective clinical audit review</atitle><jtitle>Obstetric medicine</jtitle><addtitle>Obstet Med</addtitle><date>2019-09-01</date><risdate>2019</risdate><volume>12</volume><issue>3</issue><spage>123</spage><epage>128</epage><pages>123-128</pages><issn>1753-495X</issn><eissn>1753-4968</eissn><abstract><![CDATA[Background
To determine the prevalence and outcomes of intrahepatic cholestasis of pregnancy.
Methods
A review comparing intrahepatic cholestasis of pregnancy pregnancies to all other pregnancies in three tertiary care Australian hospitals over a 36-month period.
Results
There were 43,876 pregnancies. The prevalence of intrahepatic cholestasis of pregnancies (n = 319) was 0.7%. There were differences between intrahepatic cholestasis of pregnancy and non-intrahepatic cholestasis of pregnancy mothers including higher prevalence of South Asian (22.6% versus 3.1%, p < 0.001), Indigenous Australian (3.8% versus 1.8%, p < 0.05), and Asian ethnicity (8.4% versus 5.7%, p < 0.05), mothers with a body mass index >35 kg/m2 (10.6% versus 5.5%, p < 0.001), those with diabetes mellitus (25.7% versus 9.8%, p < 0.001), and those with twin births (8.7% versus 2.2%, p < 0.001). The primary clinical outcomes of intrahepatic cholestasis of pregnancy included a median gestational age at delivery of 36.4 (SE 0.09) weeks compared to 38.6 (SE 0.01) weeks (p < 0.001), a lower birth weight (3.12 (SE 0.03) versus 3.31 kg (SE 0.03), p < 0.001), and an increase in special care nursery admissions (44.5% versus 15.3%, p < 0.001).
Conclusion
Treated intrahepatic cholestasis of pregnancy in the population described here had similar mortality outcomes although increased special care nursery admission as compared to the general population.]]></abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>31523268</pmid><doi>10.1177/1753495X18797749</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0001-7592-832X</orcidid><orcidid>https://orcid.org/0000-0001-9887-714X</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1753-495X |
| ispartof | Obstetric medicine, 2019-09, Vol.12 (3), p.123-128 |
| issn | 1753-495X 1753-4968 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6734627 |
| source | Access via SAGE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Diagnostic tests Gallbladder diseases Liver Original Pregnancy Pregnancy complications |
| title | The prevalence and pregnancy outcomes of intrahepatic cholestasis of pregnancy: A retrospective clinical audit review |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T01%3A36%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20prevalence%20and%20pregnancy%20outcomes%20of%20intrahepatic%20cholestasis%20of%20pregnancy:%20A%20retrospective%20clinical%20audit%20review&rft.jtitle=Obstetric%20medicine&rft.au=Gardiner,%20Fergus%20W&rft.date=2019-09-01&rft.volume=12&rft.issue=3&rft.spage=123&rft.epage=128&rft.pages=123-128&rft.issn=1753-495X&rft.eissn=1753-4968&rft_id=info:doi/10.1177/1753495X18797749&rft_dat=%3Cproquest_pubme%3E2299460860%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2299460860&rft_id=info:pmid/31523268&rft_sage_id=10.1177_1753495X18797749&rfr_iscdi=true |