Impaired diaphragm resistance vessel vasodilation with prolonged mechanical ventilation

Mechanical ventilation (MV) is a life-saving intervention, yet with prolonged MV (i.e., ≥6 h) there are time-dependent reductions in diaphragm blood flow and an impaired hyperemic response of unknown origin. Female Sprague-Dawley rats (4-8 mo, = 118) were randomized into two groups; spontaneous brea...

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