Noninvasive Imaging Biomarker Identifies Small Airway Damage in Severe Chronic Obstructive Pulmonary Disease

Evidence suggests damage to small airways is a key pathologic lesion in chronic obstructive pulmonary disease (COPD). Computed tomography densitometry has been demonstrated to identify emphysema, but no such studies have been performed linking an imaging metric to small airway abnormality. To correl...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2019-09, Vol.200 (5), p.575-581
Hauptverfasser:	Vasilescu, Dragoş M, Martinez, Fernando J, Marchetti, Nathaniel, Galbán, Craig J, Hatt, Charles, Meldrum, Catherine A, Dass, Chandra, Tanabe, Naoya, Reddy, Rishindra M, Lagstein, Amir, Ross, Brian D, Labaki, Wassim W, Murray, Susan, Meng, Xia, Curtis, Jeffrey L, Hackett, Tillie L, Kazerooni, Ella A, Criner, Gerard J, Hogg, James C, Han, MeiLan K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Airway Obstruction - diagnostic imaging Biomarkers Chronic obstructive pulmonary disease Collaboration Cross-Sectional Studies Emphysema Female Histology Humans Male Medical imaging Middle Aged Original Pulmonary Disease, Chronic Obstructive - physiopathology Transplants & implants X-Ray Microtomography - methods
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