Molecular and Cellular Diversity of Neuronal G-Protein-Gated Potassium Channels

Neuronal G-protein-gated potassium (GIRK) channels mediate the inhibitory effects of many neurotransmitters. Although the overlapping distribution of GIRK subunits suggests that channel composition varies in the CNS, little direct evidence supports the existence of structural or functional diversity...

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Veröffentlicht in:	The Journal of neuroscience 2005-12, Vol.25 (49), p.11468-11478
Hauptverfasser:	Koyrakh, Lev, Lujan, Rafael, Colon, Jose, Karschin, Christine, Kurachi, Yoshihisa, Karschin, Andreas, Wickman, Kevin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Baclofen - pharmacology Brain - drug effects Brain - metabolism Cellular/Molecular Dose-Response Relationship, Drug G Protein-Coupled Inwardly-Rectifying Potassium Channels - biosynthesis G Protein-Coupled Inwardly-Rectifying Potassium Channels - genetics In Vitro Techniques Male Mice Mice, Knockout Neurons - drug effects Neurons - metabolism Neurons - ultrastructure
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