Modulation of NMDA receptors by pituitary adenylate cyclase activating peptide in CA1 neurons requires G alpha q, protein kinase C, and activation of Src

At CA1 synapses, activation of NMDA receptors (NMDARs) is required for the induction of both long-term potentiation and depression. The basal level of activity of these receptors is controlled by converging cell signals from G-protein-coupled receptors and receptor tyrosine kinases. Pituitary adenyl...

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Veröffentlicht in:The Journal of neuroscience 2005-12, Vol.25 (49), p.11374-11384
Hauptverfasser: Macdonald, D S, Weerapura, M, Beazely, M A, Martin, L, Czerwinski, W, Roder, J C, Orser, B A, MacDonald, J F
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Sprache:eng
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