Identification of Glyoxalase-I as a Protein Marker in a Mouse Model of Extremes in Trait Anxiety

For >15 generations, CD1 mice have been selectively and bidirectionally bred for either high-anxiety-related behavior (HAB-M) or low-anxiety-related behavior (LAB-M) on the elevated plus-maze. Independent of gender, HAB-M were more anxious than LAB-M animals in a variety of additional tests, incl...

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Veröffentlicht in:	The Journal of neuroscience 2005-04, Vol.25 (17), p.4375-4384
Hauptverfasser:	Kromer, Simone A, Kessler, Melanie S, Milfay, Dale, Birg, Isabel N, Bunck, Mirjam, Czibere, Ludwig, Panhuysen, Markus, Putz, Benno, Deussing, Jan M, Holsboer, Florian, Landgraf, Rainer, Turck, Christoph W
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Animals, Newborn Anti-Anxiety Agents - administration & dosage Anxiety Disorders - diagnosis Anxiety Disorders - drug therapy Anxiety Disorders - enzymology Anxiety Disorders - genetics Avoidance Learning - drug effects Avoidance Learning - physiology Behavior, Animal Behavioral/Systems/Cognitive Biomarkers - metabolism Blotting, Western - methods Brain - drug effects Brain - metabolism Breeding - methods Diazepam - administration & dosage Disease Models, Animal Electrophoresis, Gel, Two-Dimensional - methods Exploratory Behavior - drug effects Exploratory Behavior - physiology Female Hindlimb Suspension - physiology Lactoylglutathione Lyase - isolation & purification Lactoylglutathione Lyase - metabolism Locomotion - genetics Male Mass Spectrometry - methods Mice Microarray Analysis - methods Phenotype Predictive Value of Tests Proteomics - methods Reaction Time - physiology Reproducibility of Results Sex Factors Spatial Behavior - drug effects Spatial Behavior - physiology Statistics as Topic Swimming Time Factors Vocalization, Animal - drug effects Vocalization, Animal - physiology
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