Disrupted placental serotonin synthetic pathway and increased placental serotonin: Potential implications in the pathogenesis of human fetal growth restriction

Placental insufficiency contributes to altered maternal-fetal amino acid transfer, and thereby to poor fetal growth. An important placental function is the uptake of tryptophan and its metabolism to serotonin (5-HT) and kynurenine metabolites, which are essential for fetal development. We hypothesis...

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Veröffentlicht in:	Placenta (Eastbourne) 2019-09, Vol.84, p.74-83
Hauptverfasser:	Ranzil, Suveena, Ellery, Stacey, Walker, David W., Vaillancourt, Cathy, Alfaidy, Nadia, Bonnin, Alexander, Borg, Anthony, Wallace, Euan M., Ebeling, Peter R., Erwich, Jan Jaap, Murthi, Padma
Format:	Artikel
Sprache:	eng
Schlagworte:	Ecology, environment Health Life Sciences
Online-Zugang:	Volltext
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