The Variant at TGFBRAP1 but Not TGFBR2 Is Associated with Antituberculosis Drug-Induced Liver Injury

Background. TGFBRAP1 and TGFBR2 play important roles in the TGF-β/smad signalling pathway and may disturb liver homeostasis by regulating liver injury and renewal. However, little is known about the association between their genetic polymorphisms and antituberculosis drug-induced liver injury (ATDIL...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2019, Vol.2019 (2019), p.1-9
Hauptverfasser:	Lyv, Mengyuan, Ying, Binwu, Song, Jiajia, Liu, Tangyuheng, Wu, Tao, Wu, Qian, Jiao, Lin, Bai, Hao, Zhao, Zhenzhen, Zhang, Jingwei, Hu, Xuejiao
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Antitubercular agents Bone morphogenetic proteins Breast cancer Cancer therapies Chemotherapy Comparative analysis Cytokines Drugs Ethylenediaminetetraacetic acid Evidence-based medicine Gene expression Growth factors Hepatitis HIV Homeostasis Human immunodeficiency virus Liver Liver cancer Liver diseases Medical research Metabolism Metabolites Pathogenesis Pathology Phosphorylation Physiology Signal transduction Single nucleotide polymorphisms Single-nucleotide polymorphism Smad protein Transforming growth factors Tuberculosis
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