High‐risk social drinkers and heavy drinkers display similar rates of alcohol consumption
Alcohol consumption is often assessed over weeks to months, but few attempts have been made to characterize alcohol consumption rates at the level of an individual drinking session. Here, we aimed to compare the rate of alcohol consumption in social drinkers at high risk for alcohol use disorder (AU...
Gespeichert in:
Veröffentlicht in: | Addiction biology 2020-03, Vol.25 (2), p.e12734-n/a |
---|---|
Hauptverfasser: | , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | n/a |
---|---|
container_issue | 2 |
container_start_page | e12734 |
container_title | Addiction biology |
container_volume | 25 |
creator | Sloan, Matthew E. Gowin, Joshua L. Janakiraman, Roshni Ester, Corbin D. Stoddard, Joel Stangl, Bethany Ramchandani, Vijay A. |
description | Alcohol consumption is often assessed over weeks to months, but few attempts have been made to characterize alcohol consumption rates at the level of an individual drinking session. Here, we aimed to compare the rate of alcohol consumption in social drinkers at high risk for alcohol use disorder (AUD) and heavy drinkers. One hundred and sixty social drinkers and 48 heavy drinkers participated in an alcohol self‐administration study. Social drinkers were classified as low risk or high risk for AUD based on sex, impulsivity, and family history of alcoholism. Participants received a priming dose of intravenous alcohol to assess alcohol‐induced craving and completed a 125‐minute intravenous alcohol self‐administration session to assess rate of achieving a binge‐level exposure (blood alcohol concentration greater than or equal to 80 mg%). There were no differences between rates of binging in high‐risk and heavy drinkers (hazard ratio = 0.87; 95% CI, 0.48‐1.56). Heavy drinkers reported higher levels of craving than high‐risk and low‐risk drinkers at baseline. However, following a priming dose of alcohol, there were no longer differences in craving between high‐risk and heavy drinkers. These results indicate that high‐risk social drinkers demonstrate binging behavior that is similar to heavy drinkers, which may be driven by alcohol‐induced craving. Prospective studies are needed to elucidate whether these patterns of craving and consumption in high‐risk social drinkers are predictive of future AUD.
Using an intravenous alcohol self‐administration paradigm, we compared rates of achieving a binge level of intoxication between heavy drinkers and social drinkers at high and low risk for alcohol use disorder. We found that high‐risk social drinkers and heavy drinkers had similar rates of alcohol consumption. Additionally, unlike low‐risk social drinkers, high‐risk social drinkers had increased craving following alcohol exposure, which may help explain their elevated levels of consumption. |
doi_str_mv | 10.1111/adb.12734 |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6717699</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2351463588</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4434-de6073698e85478cc7a4e748da4a5a2dd0e34af111f0d4a51e006f4f3a1143843</originalsourceid><addsrcrecordid>eNp1kc1OAjEUhRujEUQXvoBp4srFQDvt_LAxQfzBhMSNrlw0l2kHCsMU2xkMOx_BZ_RJLIKoC--mN7dfzj3tQeiUkjb11QE5atMwYXwPNSmLuwGNCdlf91EUxCGNGujIuSkhHorYIWowkoaUk24TPQ_0ePLx9m61m2FnMg0FllaXM2UdhlLiiYLl6mcktVsUsMJOz3UBFluolMMmx1BkZmIKnJnS1fNFpU15jA5yKJw62Z4t9HR789gfBMOHu_t-bxhknDMeSBWTxLtOVRrxJM2yBLhKeCqBQwShlEQxDrl_aE6kH1FFSJzznAGlnKWctdDlRndRj-ZKZqqsLBRiYfUc7EoY0OLvTaknYmyWIk5oEne7XuB8K2DNS61cJaamtqX3LEIWUR6zKE09dbGhMmucsyrfbaBErHMQPgfxlYNnz35b2pHfH--BzgZ41YVa_a8ketdXG8lPljaUHQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2351463588</pqid></control><display><type>article</type><title>High‐risk social drinkers and heavy drinkers display similar rates of alcohol consumption</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Sloan, Matthew E. ; Gowin, Joshua L. ; Janakiraman, Roshni ; Ester, Corbin D. ; Stoddard, Joel ; Stangl, Bethany ; Ramchandani, Vijay A.</creator><creatorcontrib>Sloan, Matthew E. ; Gowin, Joshua L. ; Janakiraman, Roshni ; Ester, Corbin D. ; Stoddard, Joel ; Stangl, Bethany ; Ramchandani, Vijay A.</creatorcontrib><description>Alcohol consumption is often assessed over weeks to months, but few attempts have been made to characterize alcohol consumption rates at the level of an individual drinking session. Here, we aimed to compare the rate of alcohol consumption in social drinkers at high risk for alcohol use disorder (AUD) and heavy drinkers. One hundred and sixty social drinkers and 48 heavy drinkers participated in an alcohol self‐administration study. Social drinkers were classified as low risk or high risk for AUD based on sex, impulsivity, and family history of alcoholism. Participants received a priming dose of intravenous alcohol to assess alcohol‐induced craving and completed a 125‐minute intravenous alcohol self‐administration session to assess rate of achieving a binge‐level exposure (blood alcohol concentration greater than or equal to 80 mg%). There were no differences between rates of binging in high‐risk and heavy drinkers (hazard ratio = 0.87; 95% CI, 0.48‐1.56). Heavy drinkers reported higher levels of craving than high‐risk and low‐risk drinkers at baseline. However, following a priming dose of alcohol, there were no longer differences in craving between high‐risk and heavy drinkers. These results indicate that high‐risk social drinkers demonstrate binging behavior that is similar to heavy drinkers, which may be driven by alcohol‐induced craving. Prospective studies are needed to elucidate whether these patterns of craving and consumption in high‐risk social drinkers are predictive of future AUD.
Using an intravenous alcohol self‐administration paradigm, we compared rates of achieving a binge level of intoxication between heavy drinkers and social drinkers at high and low risk for alcohol use disorder. We found that high‐risk social drinkers and heavy drinkers had similar rates of alcohol consumption. Additionally, unlike low‐risk social drinkers, high‐risk social drinkers had increased craving following alcohol exposure, which may help explain their elevated levels of consumption.</description><identifier>ISSN: 1355-6215</identifier><identifier>EISSN: 1369-1600</identifier><identifier>DOI: 10.1111/adb.12734</identifier><identifier>PMID: 30821409</identifier><language>eng</language><publisher>United States: John Wiley & Sons, Inc</publisher><subject>addictive behavior ; Adult ; Alcohol Drinking - epidemiology ; alcohol self‐administration ; Alcohol use ; Alcoholism ; Alcoholism - epidemiology ; binge drinking ; Binge Drinking - epidemiology ; Blood levels ; craving ; Craving - drug effects ; Drinking behavior ; Drug abuse ; Ethanol - administration & dosage ; Ethanol - pharmacology ; Female ; Genetic Predisposition to Disease ; Humans ; Impulsive Behavior ; Intravenous administration ; Male ; Risk ; risk factors ; Self Administration ; Sex Factors ; Social behavior ; Young Adult</subject><ispartof>Addiction biology, 2020-03, Vol.25 (2), p.e12734-n/a</ispartof><rights>2019 Society for the Study of Addiction</rights><rights>2019 Society for the Study of Addiction.</rights><rights>2020 Society for the Study of Addiction</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4434-de6073698e85478cc7a4e748da4a5a2dd0e34af111f0d4a51e006f4f3a1143843</citedby><cites>FETCH-LOGICAL-c4434-de6073698e85478cc7a4e748da4a5a2dd0e34af111f0d4a51e006f4f3a1143843</cites><orcidid>0000-0003-2172-8802</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fadb.12734$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fadb.12734$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,780,784,885,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30821409$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sloan, Matthew E.</creatorcontrib><creatorcontrib>Gowin, Joshua L.</creatorcontrib><creatorcontrib>Janakiraman, Roshni</creatorcontrib><creatorcontrib>Ester, Corbin D.</creatorcontrib><creatorcontrib>Stoddard, Joel</creatorcontrib><creatorcontrib>Stangl, Bethany</creatorcontrib><creatorcontrib>Ramchandani, Vijay A.</creatorcontrib><title>High‐risk social drinkers and heavy drinkers display similar rates of alcohol consumption</title><title>Addiction biology</title><addtitle>Addict Biol</addtitle><description>Alcohol consumption is often assessed over weeks to months, but few attempts have been made to characterize alcohol consumption rates at the level of an individual drinking session. Here, we aimed to compare the rate of alcohol consumption in social drinkers at high risk for alcohol use disorder (AUD) and heavy drinkers. One hundred and sixty social drinkers and 48 heavy drinkers participated in an alcohol self‐administration study. Social drinkers were classified as low risk or high risk for AUD based on sex, impulsivity, and family history of alcoholism. Participants received a priming dose of intravenous alcohol to assess alcohol‐induced craving and completed a 125‐minute intravenous alcohol self‐administration session to assess rate of achieving a binge‐level exposure (blood alcohol concentration greater than or equal to 80 mg%). There were no differences between rates of binging in high‐risk and heavy drinkers (hazard ratio = 0.87; 95% CI, 0.48‐1.56). Heavy drinkers reported higher levels of craving than high‐risk and low‐risk drinkers at baseline. However, following a priming dose of alcohol, there were no longer differences in craving between high‐risk and heavy drinkers. These results indicate that high‐risk social drinkers demonstrate binging behavior that is similar to heavy drinkers, which may be driven by alcohol‐induced craving. Prospective studies are needed to elucidate whether these patterns of craving and consumption in high‐risk social drinkers are predictive of future AUD.
Using an intravenous alcohol self‐administration paradigm, we compared rates of achieving a binge level of intoxication between heavy drinkers and social drinkers at high and low risk for alcohol use disorder. We found that high‐risk social drinkers and heavy drinkers had similar rates of alcohol consumption. Additionally, unlike low‐risk social drinkers, high‐risk social drinkers had increased craving following alcohol exposure, which may help explain their elevated levels of consumption.</description><subject>addictive behavior</subject><subject>Adult</subject><subject>Alcohol Drinking - epidemiology</subject><subject>alcohol self‐administration</subject><subject>Alcohol use</subject><subject>Alcoholism</subject><subject>Alcoholism - epidemiology</subject><subject>binge drinking</subject><subject>Binge Drinking - epidemiology</subject><subject>Blood levels</subject><subject>craving</subject><subject>Craving - drug effects</subject><subject>Drinking behavior</subject><subject>Drug abuse</subject><subject>Ethanol - administration & dosage</subject><subject>Ethanol - pharmacology</subject><subject>Female</subject><subject>Genetic Predisposition to Disease</subject><subject>Humans</subject><subject>Impulsive Behavior</subject><subject>Intravenous administration</subject><subject>Male</subject><subject>Risk</subject><subject>risk factors</subject><subject>Self Administration</subject><subject>Sex Factors</subject><subject>Social behavior</subject><subject>Young Adult</subject><issn>1355-6215</issn><issn>1369-1600</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc1OAjEUhRujEUQXvoBp4srFQDvt_LAxQfzBhMSNrlw0l2kHCsMU2xkMOx_BZ_RJLIKoC--mN7dfzj3tQeiUkjb11QE5atMwYXwPNSmLuwGNCdlf91EUxCGNGujIuSkhHorYIWowkoaUk24TPQ_0ePLx9m61m2FnMg0FllaXM2UdhlLiiYLl6mcktVsUsMJOz3UBFluolMMmx1BkZmIKnJnS1fNFpU15jA5yKJw62Z4t9HR789gfBMOHu_t-bxhknDMeSBWTxLtOVRrxJM2yBLhKeCqBQwShlEQxDrl_aE6kH1FFSJzznAGlnKWctdDlRndRj-ZKZqqsLBRiYfUc7EoY0OLvTaknYmyWIk5oEne7XuB8K2DNS61cJaamtqX3LEIWUR6zKE09dbGhMmucsyrfbaBErHMQPgfxlYNnz35b2pHfH--BzgZ41YVa_a8ketdXG8lPljaUHQ</recordid><startdate>202003</startdate><enddate>202003</enddate><creator>Sloan, Matthew E.</creator><creator>Gowin, Joshua L.</creator><creator>Janakiraman, Roshni</creator><creator>Ester, Corbin D.</creator><creator>Stoddard, Joel</creator><creator>Stangl, Bethany</creator><creator>Ramchandani, Vijay A.</creator><general>John Wiley & Sons, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7T5</scope><scope>7TM</scope><scope>H94</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-2172-8802</orcidid></search><sort><creationdate>202003</creationdate><title>High‐risk social drinkers and heavy drinkers display similar rates of alcohol consumption</title><author>Sloan, Matthew E. ; Gowin, Joshua L. ; Janakiraman, Roshni ; Ester, Corbin D. ; Stoddard, Joel ; Stangl, Bethany ; Ramchandani, Vijay A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4434-de6073698e85478cc7a4e748da4a5a2dd0e34af111f0d4a51e006f4f3a1143843</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>addictive behavior</topic><topic>Adult</topic><topic>Alcohol Drinking - epidemiology</topic><topic>alcohol self‐administration</topic><topic>Alcohol use</topic><topic>Alcoholism</topic><topic>Alcoholism - epidemiology</topic><topic>binge drinking</topic><topic>Binge Drinking - epidemiology</topic><topic>Blood levels</topic><topic>craving</topic><topic>Craving - drug effects</topic><topic>Drinking behavior</topic><topic>Drug abuse</topic><topic>Ethanol - administration & dosage</topic><topic>Ethanol - pharmacology</topic><topic>Female</topic><topic>Genetic Predisposition to Disease</topic><topic>Humans</topic><topic>Impulsive Behavior</topic><topic>Intravenous administration</topic><topic>Male</topic><topic>Risk</topic><topic>risk factors</topic><topic>Self Administration</topic><topic>Sex Factors</topic><topic>Social behavior</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sloan, Matthew E.</creatorcontrib><creatorcontrib>Gowin, Joshua L.</creatorcontrib><creatorcontrib>Janakiraman, Roshni</creatorcontrib><creatorcontrib>Ester, Corbin D.</creatorcontrib><creatorcontrib>Stoddard, Joel</creatorcontrib><creatorcontrib>Stangl, Bethany</creatorcontrib><creatorcontrib>Ramchandani, Vijay A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Immunology Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Addiction biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sloan, Matthew E.</au><au>Gowin, Joshua L.</au><au>Janakiraman, Roshni</au><au>Ester, Corbin D.</au><au>Stoddard, Joel</au><au>Stangl, Bethany</au><au>Ramchandani, Vijay A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>High‐risk social drinkers and heavy drinkers display similar rates of alcohol consumption</atitle><jtitle>Addiction biology</jtitle><addtitle>Addict Biol</addtitle><date>2020-03</date><risdate>2020</risdate><volume>25</volume><issue>2</issue><spage>e12734</spage><epage>n/a</epage><pages>e12734-n/a</pages><issn>1355-6215</issn><eissn>1369-1600</eissn><abstract>Alcohol consumption is often assessed over weeks to months, but few attempts have been made to characterize alcohol consumption rates at the level of an individual drinking session. Here, we aimed to compare the rate of alcohol consumption in social drinkers at high risk for alcohol use disorder (AUD) and heavy drinkers. One hundred and sixty social drinkers and 48 heavy drinkers participated in an alcohol self‐administration study. Social drinkers were classified as low risk or high risk for AUD based on sex, impulsivity, and family history of alcoholism. Participants received a priming dose of intravenous alcohol to assess alcohol‐induced craving and completed a 125‐minute intravenous alcohol self‐administration session to assess rate of achieving a binge‐level exposure (blood alcohol concentration greater than or equal to 80 mg%). There were no differences between rates of binging in high‐risk and heavy drinkers (hazard ratio = 0.87; 95% CI, 0.48‐1.56). Heavy drinkers reported higher levels of craving than high‐risk and low‐risk drinkers at baseline. However, following a priming dose of alcohol, there were no longer differences in craving between high‐risk and heavy drinkers. These results indicate that high‐risk social drinkers demonstrate binging behavior that is similar to heavy drinkers, which may be driven by alcohol‐induced craving. Prospective studies are needed to elucidate whether these patterns of craving and consumption in high‐risk social drinkers are predictive of future AUD.
Using an intravenous alcohol self‐administration paradigm, we compared rates of achieving a binge level of intoxication between heavy drinkers and social drinkers at high and low risk for alcohol use disorder. We found that high‐risk social drinkers and heavy drinkers had similar rates of alcohol consumption. Additionally, unlike low‐risk social drinkers, high‐risk social drinkers had increased craving following alcohol exposure, which may help explain their elevated levels of consumption.</abstract><cop>United States</cop><pub>John Wiley & Sons, Inc</pub><pmid>30821409</pmid><doi>10.1111/adb.12734</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0003-2172-8802</orcidid><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1355-6215 |
ispartof | Addiction biology, 2020-03, Vol.25 (2), p.e12734-n/a |
issn | 1355-6215 1369-1600 |
language | eng |
recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6717699 |
source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
subjects | addictive behavior Adult Alcohol Drinking - epidemiology alcohol self‐administration Alcohol use Alcoholism Alcoholism - epidemiology binge drinking Binge Drinking - epidemiology Blood levels craving Craving - drug effects Drinking behavior Drug abuse Ethanol - administration & dosage Ethanol - pharmacology Female Genetic Predisposition to Disease Humans Impulsive Behavior Intravenous administration Male Risk risk factors Self Administration Sex Factors Social behavior Young Adult |
title | High‐risk social drinkers and heavy drinkers display similar rates of alcohol consumption |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T16%3A04%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=High%E2%80%90risk%20social%20drinkers%20and%20heavy%20drinkers%20display%20similar%20rates%20of%20alcohol%20consumption&rft.jtitle=Addiction%20biology&rft.au=Sloan,%20Matthew%20E.&rft.date=2020-03&rft.volume=25&rft.issue=2&rft.spage=e12734&rft.epage=n/a&rft.pages=e12734-n/a&rft.issn=1355-6215&rft.eissn=1369-1600&rft_id=info:doi/10.1111/adb.12734&rft_dat=%3Cproquest_pubme%3E2351463588%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2351463588&rft_id=info:pmid/30821409&rfr_iscdi=true |