CAR T cell therapy for B-cell lymphomas

B-cell non-Hodgkin's lymphoma (NHLs)is a very heterogonous malignancy with diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) as the most common subtypes. Standard treatment with anti-CD20 based chemoimmunotherapy is usually very effective for disease control. However a signific...

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Veröffentlicht in:	Best practice & research. Clinical haematology 2018-06, Vol.31 (2), p.135-146
Hauptverfasser:	Chavez, Julio C., Locke, Frederick L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aggressive lymphomas Antigens, CD19 - immunology CART Diffuse large B cell lymphoma Humans Immunotherapy Immunotherapy, Adoptive - methods Lymphoma, Follicular - immunology Lymphoma, Follicular - pathology Lymphoma, Follicular - therapy Lymphoma, Large B-Cell, Diffuse - immunology Lymphoma, Large B-Cell, Diffuse - pathology Lymphoma, Large B-Cell, Diffuse - therapy Multicenter Studies as Topic Receptors, Chimeric Antigen - immunology Receptors, Chimeric Antigen - therapeutic use Refractory Risk Factors
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