Respiration of permeabilized cardiomyocytes from mice: no sex differences, but substrate-dependent changes in the apparent ADP-affinity

Sex differences in cardiac physiology are getting increased attention. This study assessed whether isolated, permeabilized cardiomyocytes from male and female C57BL/6 mice differ in terms of their respiration with multiple substrates and overall intracellular diffusion restriction estimated by the a...

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Veröffentlicht in:	Scientific reports 2019-08, Vol.9 (1), p.12592-11, Article 12592
Hauptverfasser:	Karro, Niina, Laasmaa, Martin, Vendelin, Marko, Birkedal, Rikke
Format:	Artikel
Sprache:	eng
Schlagworte:	13 631/443/592 631/80/642/333/1465 64/60 9/10 Adenosine Diphosphate - metabolism Affinity Animals Cardiomyocytes Cell Respiration Citrate synthase Female Gender differences Humanities and Social Sciences Intracellular Male Mice Mice, Inbred C57BL Mitochondria multidisciplinary Myocytes, Cardiac - cytology Myocytes, Cardiac - metabolism Permeability Pyruvic acid Respiration Science Science (multidisciplinary) Sex Characteristics Sex differences Substrates
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