Circulating but not faecal short-chain fatty acids are related to insulin sensitivity, lipolysis and GLP-1 concentrations in humans

Microbial-derived short-chain fatty acids (SCFA) acetate, propionate and butyrate may provide a link between gut microbiota and whole-body insulin sensitivity (IS). In this cross-sectional study (160 participants, 64% male, BMI: 19.2–41.0 kg/m 2 , normal or impaired glucose metabolism), associations...

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Veröffentlicht in:	Scientific reports 2019-08, Vol.9 (1), p.12515-9, Article 12515
Hauptverfasser:	Müller, Mattea, Hernández, Manuel A. González, Goossens, Gijs H., Reijnders, Dorien, Holst, Jens J., Jocken, Johan W. E., van Eijk, Hans, Canfora, Emanuel E., Blaak, Ellen E.
Format:	Artikel
Sprache:	eng
Schlagworte:	692/163/2743/2037 692/4020/198 82/16 Acetic acid Adult Aged Cross-Sectional Studies Dietary fiber Fasting Fatty acids Fatty Acids, Volatile - analysis Fatty Acids, Volatile - blood Feces - chemistry Female Gastrointestinal Microbiome Glucagon-Like Peptide 1 - blood Glucose metabolism Glycerol Humanities and Social Sciences Humans Insulin Insulin - blood Insulin Resistance Intestinal microflora Laboratory testing Lipolysis Male Metabolism Metabolites Microbiota Middle Aged multidisciplinary Oxidation Probiotics Propionic acid Regression analysis Science Science (multidisciplinary) Young Adult
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