Buccal mucosal graft versus penile skin flap urethroplasty for long segment penile urethral stricture: a prospective randomized study
The aim of this study was to analyze the outcomes of dorsolateral onlay buccal mucosal graft (BMG) and ventral onlay local penile skin flap (LPF) urethroplasty in the management of long segment penile urethral stricture (PUS). Through a prospective study conducted between October 2014 and May 2018,...
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Veröffentlicht in: | Central European journal of urology 2019-01, Vol.72 (2), p.191-197 |
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container_title | Central European journal of urology |
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creator | Ali, Ahmed Issam Hamid, Amr Abdel Abdel-Rassoul, Mohammed Abdou Galal, Ehab M Hasanein, Mohammed G S Hassan, Mohamed Abd Elmalek El-Hawy, Mamdouh M |
description | The aim of this study was to analyze the outcomes of dorsolateral onlay buccal mucosal graft (BMG) and ventral onlay local penile skin flap (LPF) urethroplasty in the management of long segment penile urethral stricture (PUS).
Through a prospective study conducted between October 2014 and May 2018, 84 patients with long segment PUS were randomly assigned to receive either dorsolateral onlay BMG (Group 1 which included 42 patients) or ventral onlay PSF urethroplasty (Group 2 which included 42 patients). The success rate and surgical outcomes were compared in both groups.
The success rate was 92.9% in Group 1 and 85.7% in Group 2 (p = 0.5). Postoperative short segment urethral stricture at the site of proximal anastomosis was reported in 3 patients in Group 1. Six patients in Group 2 were considered as a treatment failure, 3 of them due to recurrence of long segment urethral stricture after 6 months, and 3 patients developed ring urethral stricture at the site of proximal anastomosis managed by direct vision internal urethrotomy.
On an intermediate term follow-up, dorsolateral onlay BMG and ventral onlay LPF provide similar success rates in penile urethroplasty, with essentially comparable postoperative morbidity. However, further studies with bigger sample sizes and longer follow-up periods may be required to determine subtle differences between both techniques. |
doi_str_mv | 10.5173/ceju.2019.1899 |
format | Article |
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Through a prospective study conducted between October 2014 and May 2018, 84 patients with long segment PUS were randomly assigned to receive either dorsolateral onlay BMG (Group 1 which included 42 patients) or ventral onlay PSF urethroplasty (Group 2 which included 42 patients). The success rate and surgical outcomes were compared in both groups.
The success rate was 92.9% in Group 1 and 85.7% in Group 2 (p = 0.5). Postoperative short segment urethral stricture at the site of proximal anastomosis was reported in 3 patients in Group 1. Six patients in Group 2 were considered as a treatment failure, 3 of them due to recurrence of long segment urethral stricture after 6 months, and 3 patients developed ring urethral stricture at the site of proximal anastomosis managed by direct vision internal urethrotomy.
On an intermediate term follow-up, dorsolateral onlay BMG and ventral onlay LPF provide similar success rates in penile urethroplasty, with essentially comparable postoperative morbidity. However, further studies with bigger sample sizes and longer follow-up periods may be required to determine subtle differences between both techniques.</description><identifier>ISSN: 2080-4806</identifier><identifier>ISSN: 2080-4873</identifier><identifier>EISSN: 2080-4873</identifier><identifier>DOI: 10.5173/ceju.2019.1899</identifier><identifier>PMID: 31482029</identifier><language>eng</language><publisher>Poland: Polish Urological Association</publisher><subject>Hospitals ; Original Paper ; Skin & tissue grafts ; Studies ; Success ; Surgical outcomes ; Surgical techniques ; Ultrasonic imaging ; Urine ; Urology</subject><ispartof>Central European journal of urology, 2019-01, Vol.72 (2), p.191-197</ispartof><rights>Copyright Polish Urological Association 2019</rights><rights>Copyright by Polish Urological Association 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c418t-dd32bd3e7b9b2b2c212364704aee868406f9c987bb9b0daafba8da1788c6240e3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715090/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715090/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31482029$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ali, Ahmed Issam</creatorcontrib><creatorcontrib>Hamid, Amr Abdel</creatorcontrib><creatorcontrib>Abdel-Rassoul, Mohammed Abdou</creatorcontrib><creatorcontrib>Galal, Ehab M</creatorcontrib><creatorcontrib>Hasanein, Mohammed G S</creatorcontrib><creatorcontrib>Hassan, Mohamed Abd Elmalek</creatorcontrib><creatorcontrib>El-Hawy, Mamdouh M</creatorcontrib><title>Buccal mucosal graft versus penile skin flap urethroplasty for long segment penile urethral stricture: a prospective randomized study</title><title>Central European journal of urology</title><addtitle>Cent European J Urol</addtitle><description>The aim of this study was to analyze the outcomes of dorsolateral onlay buccal mucosal graft (BMG) and ventral onlay local penile skin flap (LPF) urethroplasty in the management of long segment penile urethral stricture (PUS).
Through a prospective study conducted between October 2014 and May 2018, 84 patients with long segment PUS were randomly assigned to receive either dorsolateral onlay BMG (Group 1 which included 42 patients) or ventral onlay PSF urethroplasty (Group 2 which included 42 patients). The success rate and surgical outcomes were compared in both groups.
The success rate was 92.9% in Group 1 and 85.7% in Group 2 (p = 0.5). Postoperative short segment urethral stricture at the site of proximal anastomosis was reported in 3 patients in Group 1. Six patients in Group 2 were considered as a treatment failure, 3 of them due to recurrence of long segment urethral stricture after 6 months, and 3 patients developed ring urethral stricture at the site of proximal anastomosis managed by direct vision internal urethrotomy.
On an intermediate term follow-up, dorsolateral onlay BMG and ventral onlay LPF provide similar success rates in penile urethroplasty, with essentially comparable postoperative morbidity. However, further studies with bigger sample sizes and longer follow-up periods may be required to determine subtle differences between both techniques.</description><subject>Hospitals</subject><subject>Original Paper</subject><subject>Skin & tissue grafts</subject><subject>Studies</subject><subject>Success</subject><subject>Surgical outcomes</subject><subject>Surgical techniques</subject><subject>Ultrasonic imaging</subject><subject>Urine</subject><subject>Urology</subject><issn>2080-4806</issn><issn>2080-4873</issn><issn>2080-4873</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpdkUlvFDEQhVsIRKKQK0dkiQuXGbx0e-GABFFYpEhckrPltqsnHrrbjZeRhjv_Ox5NMgJ8KZfq81M9v6Z5TfC6I4K9t7Ata4qJWhOp1LPmnGKJV60U7PnpjvlZc5nSFtfDZcu77mVzxkgrKabqvPnzuVhrRjQVG1Ktm2iGjHYQU0logdmPgNJPP6NhNAsqEfJ9DMtoUt6jIUQ0hnmDEmwmmPMTf6SqWMrR21zbD8igJYa0gM1-Byia2YXJ_wZXmeL2r5oXgxkTXD7Wi-buy_Xt1bfVzY-v368-3axsS2ReOcdo7xiIXvW0p5YSyngrcGsAZDWH-aCskqKvc-yMGXojnSFCSstpi4FdNB-PukvpJ3C2Ll331Ev0k4l7HYzX_05mf683Yae5IB1WuAq8exSI4VeBlPXkk4VxNDOEkjSlsu04FkpU9O1_6DaUOFd7leJScYkVq9T6SNn6PSnCcFqGYH0IWR9C1oeQ9SHk-uDN3xZO-FOk7AFGl6eb</recordid><startdate>20190101</startdate><enddate>20190101</enddate><creator>Ali, Ahmed Issam</creator><creator>Hamid, Amr Abdel</creator><creator>Abdel-Rassoul, Mohammed Abdou</creator><creator>Galal, Ehab M</creator><creator>Hasanein, Mohammed G S</creator><creator>Hassan, Mohamed Abd Elmalek</creator><creator>El-Hawy, Mamdouh M</creator><general>Polish Urological Association</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BYOGL</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20190101</creationdate><title>Buccal mucosal graft versus penile skin flap urethroplasty for long segment penile urethral stricture: a prospective randomized study</title><author>Ali, Ahmed Issam ; Hamid, Amr Abdel ; Abdel-Rassoul, Mohammed Abdou ; Galal, Ehab M ; Hasanein, Mohammed G S ; Hassan, Mohamed Abd Elmalek ; El-Hawy, Mamdouh M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c418t-dd32bd3e7b9b2b2c212364704aee868406f9c987bb9b0daafba8da1788c6240e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Hospitals</topic><topic>Original Paper</topic><topic>Skin & tissue grafts</topic><topic>Studies</topic><topic>Success</topic><topic>Surgical outcomes</topic><topic>Surgical techniques</topic><topic>Ultrasonic imaging</topic><topic>Urine</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ali, Ahmed Issam</creatorcontrib><creatorcontrib>Hamid, Amr Abdel</creatorcontrib><creatorcontrib>Abdel-Rassoul, Mohammed Abdou</creatorcontrib><creatorcontrib>Galal, Ehab M</creatorcontrib><creatorcontrib>Hasanein, Mohammed G S</creatorcontrib><creatorcontrib>Hassan, Mohamed Abd Elmalek</creatorcontrib><creatorcontrib>El-Hawy, Mamdouh M</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>East Europe, Central Europe Database</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Central European journal of urology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ali, Ahmed Issam</au><au>Hamid, Amr Abdel</au><au>Abdel-Rassoul, Mohammed Abdou</au><au>Galal, Ehab M</au><au>Hasanein, Mohammed G S</au><au>Hassan, Mohamed Abd Elmalek</au><au>El-Hawy, Mamdouh M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Buccal mucosal graft versus penile skin flap urethroplasty for long segment penile urethral stricture: a prospective randomized study</atitle><jtitle>Central European journal of urology</jtitle><addtitle>Cent European J Urol</addtitle><date>2019-01-01</date><risdate>2019</risdate><volume>72</volume><issue>2</issue><spage>191</spage><epage>197</epage><pages>191-197</pages><issn>2080-4806</issn><issn>2080-4873</issn><eissn>2080-4873</eissn><abstract>The aim of this study was to analyze the outcomes of dorsolateral onlay buccal mucosal graft (BMG) and ventral onlay local penile skin flap (LPF) urethroplasty in the management of long segment penile urethral stricture (PUS).
Through a prospective study conducted between October 2014 and May 2018, 84 patients with long segment PUS were randomly assigned to receive either dorsolateral onlay BMG (Group 1 which included 42 patients) or ventral onlay PSF urethroplasty (Group 2 which included 42 patients). The success rate and surgical outcomes were compared in both groups.
The success rate was 92.9% in Group 1 and 85.7% in Group 2 (p = 0.5). Postoperative short segment urethral stricture at the site of proximal anastomosis was reported in 3 patients in Group 1. Six patients in Group 2 were considered as a treatment failure, 3 of them due to recurrence of long segment urethral stricture after 6 months, and 3 patients developed ring urethral stricture at the site of proximal anastomosis managed by direct vision internal urethrotomy.
On an intermediate term follow-up, dorsolateral onlay BMG and ventral onlay LPF provide similar success rates in penile urethroplasty, with essentially comparable postoperative morbidity. However, further studies with bigger sample sizes and longer follow-up periods may be required to determine subtle differences between both techniques.</abstract><cop>Poland</cop><pub>Polish Urological Association</pub><pmid>31482029</pmid><doi>10.5173/ceju.2019.1899</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Hospitals Original Paper Skin & tissue grafts Studies Success Surgical outcomes Surgical techniques Ultrasonic imaging Urine Urology |
title | Buccal mucosal graft versus penile skin flap urethroplasty for long segment penile urethral stricture: a prospective randomized study |
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