Predicting pathologic response to neoadjuvant chemoradiation in resectable stage III non-small cell lung cancer patients using computed tomography radiomic features

•Tumoral heterogeneity is associated with more aggressive tumor phenotype.•Stage III N2 non-small cell lung cancer is a heterogeneous disease.•Major pathologic response is associated with amended overall survival, following NAC.•Compared to clinicopathologic variables, texture features are associate...

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Veröffentlicht in:	Lung cancer (Amsterdam, Netherlands) Netherlands), 2019-09, Vol.135, p.1-9
Hauptverfasser:	Khorrami, Mohammadhadi, Jain, Prantesh, Bera, Kaustav, Alilou, Mehdi, Thawani, Rajat, Patil, Pradnya, Ahmad, Usman, Murthy, Sudish, Stephans, Kevin, Fu, Pinfu, Velcheti, Vamsidhar, Madabhushi, Anant
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Carcinoma, Non-Small-Cell Lung - diagnosis Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - therapy Chemoradiation Chemoradiotherapy - adverse effects Chemoradiotherapy - methods Female Gene Expression Profiling Humans Image Processing, Computer-Assisted Kaplan-Meier Estimate Locally advanced Lung Neoplasms - diagnosis Lung Neoplasms - mortality Lung Neoplasms - therapy Male Middle Aged Neoadjuvant Therapy Neoplasm Metastasis Neoplasm Staging Non-small cell lung cancer Prognosis Proportional Hazards Models Radiometry Surgery Tomography, X-Ray Computed - methods Treatment Outcome
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