Manipulating a "cocaine engram" in mice

Experience with drugs of abuse (such as cocaine) produces powerful, long-lasting memories that may be important in the development and persistence of drug addiction. The neural mechanisms that mediate how and where these cocaine memories are encoded, consolidated and stored are unknown. Here we used...

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Veröffentlicht in:	The Journal of neuroscience 2014-10, Vol.34 (42), p.14115-14127
Hauptverfasser:	Hsiang, Hwa-Lin Liz, Epp, Jonathan R, van den Oever, Michel C, Yan, Chen, Rashid, Asim J, Insel, Nathan, Ye, Li, Niibori, Yosuke, Deisseroth, Karl, Frankland, Paul W, Josselyn, Sheena A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amygdala - drug effects Amygdala - metabolism Animals Cocaine - administration & dosage Conditioning (Psychology) - drug effects Conditioning (Psychology) - physiology Cyclic AMP Response Element-Binding Protein - biosynthesis Female Male Mice Mice, 129 Strain Mice, Inbred C57BL Mice, Transgenic
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