A Thermogenic-Like Brown Adipose Tissue Phenotype Is Dispensable for Enhanced Glucose Tolerance in Female Mice

The prevailing dogma is that thermogenic brown adipose tissue (BAT) contributes to improvements in glucose homeostasis in obesogenic animal models, though much of the evidence supporting this premise is from thermostressed rodents. Determination of whether modulation of the BAT morphology/function d...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2019-09, Vol.68 (9), p.1717-1729
Hauptverfasser:	Winn, Nathan C, Acin-Perez, Rebeca, Woodford, Makenzie L, Hansen, Sarah A, Haney, Megan M, Ayedun, Lolade A, Rector, R Scott, Vieira-Potter, Victoria J, Shirihai, Orian S, Sacks, Harold S, Kanaley, Jill A, Padilla, Jaume
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue (brown) Adipose Tissue, Brown - metabolism Animal models Animals Chromium Cold Temperature Cold tolerance Cold-Shock Response - physiology Diet, High-Fat Energy Metabolism - physiology Female Genotype & phenotype Glucose Glucose tolerance Glucose Tolerance Test Homeostasis Lipase - genetics Lipase - metabolism Low fat diet Metabolism Mice Mice, Knockout Nutrient deficiency Obesity - metabolism Phenotype Phenotypes Thermogenesis - physiology
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