PI31 Is an Adaptor Protein for Proteasome Transport in Axons and Required for Synaptic Development

Protein degradation by the ubiquitin-proteasome system is critical for neuronal function. Neurons utilize microtubule-dependent molecular motors to allocate proteasomes to synapses, but how proteasomes are coupled to motors and how this is regulated to meet changing demand for protein breakdown rema...

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