ROS Generation and Antioxidant Defense Systems in Normal and Malignant Cells

Reactive oxygen species (ROS) are by-products of normal cell activity. They are produced in many cellular compartments and play a major role in signaling pathways. Overproduction of ROS is associated with the development of various human diseases (including cancer, cardiovascular, neurodegenerative,...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2019, Vol.2019 (2019), p.1-17
Hauptverfasser:	Dmitriev, Alexey A., Melnikova, Nataliya V., Savvateeva, Maria V., Kardymon, Olga L., Kudryavtseva, Anna V., Snezhkina, Anastasiya V., Krasnov, George S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Antioxidants - pharmacology Antioxidants - therapeutic use Cancer therapies Cell Count Cell death Cell Transformation, Neoplastic - metabolism Cells Cytochrome Defense industry Dehydrogenases Deoxyribonucleic acid DNA Enzymes Genetic aspects Genomes Glycerol Humans Hydrogen peroxide Metabolism Mitochondria Mitochondrial DNA Oxidation Oxidative stress Physiological aspects Polyamines Reactive oxygen species Reactive Oxygen Species - metabolism Review
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