Major imbalance of thyroid function after laparoscopic sleeve gastrectomy

In patients with substituted hypothyroidism, laparoscopic sleeve gastrectomy may interfere with thyroid balance by varying body weight or by altering the absorption of hormone therapy. A 58-year-old female patient presented with a major thyroid imbalance after sleeve gastrectomy, manifesting itself...

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Veröffentlicht in:BMJ case reports 2019-08, Vol.12 (8), p.e230515
Hauptverfasser: Brutus, Laurent, Poupard, Armelle, Le Glatin, Clément
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Poupard, Armelle
Le Glatin, Clément
description In patients with substituted hypothyroidism, laparoscopic sleeve gastrectomy may interfere with thyroid balance by varying body weight or by altering the absorption of hormone therapy. A 58-year-old female patient presented with a major thyroid imbalance after sleeve gastrectomy, manifesting itself in large-scale changes in thyroid stimulating hormone (TSH) levels. The transition from a tablet treatment to a liquid form alleviated burden of treatment, unfortunately without normalising TSH. Our case emphasises the importance of the understanding of hypothalamic–pituitary–thyroid feedback control mechanisms together with good galenic choice, management of associated conditions and the elimination of other causes of variations of TSH levels during the management of hypothyroid patients after sleeve gastrectomy.
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A 58-year-old female patient presented with a major thyroid imbalance after sleeve gastrectomy, manifesting itself in large-scale changes in thyroid stimulating hormone (TSH) levels. The transition from a tablet treatment to a liquid form alleviated burden of treatment, unfortunately without normalising TSH. 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subjects Case reports
Dose-Response Relationship, Drug
Drug dosages
Female
Gastrectomy - adverse effects
Gastric Bypass - adverse effects
Gastrointestinal surgery
Hormone replacement therapy
Hormone Replacement Therapy - methods
Humans
Hypothyroidism
Hypothyroidism - blood
Hypothyroidism - drug therapy
Laparoscopy
Middle Aged
Multiple sclerosis
Obesity
Obesity, Morbid - surgery
Patients
Stomach
Thyroid gland
Thyrotropin - blood
Thyroxine - administration & dosage
Thyroxine - blood
Unusual Association of Diseases/Symptoms
Weight control
title Major imbalance of thyroid function after laparoscopic sleeve gastrectomy
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