Melatonin prevents chronic intermittent hypoxia-induced injury by inducing sirtuin 1-mediated autophagy in steatotic liver of mice

Background Hepatic steatosis that occasionally results in nonalcoholic steatohepatitis (NASH) is related to obstructive sleep apnea (OSA). Many studies have shown that autophagy exerts protective effects on liver damage caused by various diseases and melatonin exhibits hepatoprotective properties. H...

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Veröffentlicht in:Sleep & breathing 2019-09, Vol.23 (3), p.825-836
Hauptverfasser: Ren, Jie, Jin, Meng, You, Zhen-xi, Luo, Miao, Han, Yin, Li, Guang-cai, Liu, Hui-guo
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Sprache:eng
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