Late Brain Involvement after Neonatal Immune Activation

The neonatal immune system is still immature, which makes it more susceptible to the infectious agents. Neonatal immune activation is associated with increased permeability of the blood-brain barrier, causing an inflammatory cascade in the CNS and altering behavioral and neurochemical parameters. On...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BioMed research international 2019, Vol.2019 (2019), p.1-11
Hauptverfasser:	Comim, Clarissa M., Dutra, Matheus L., Bragagnolo, Daiane, Ventura, Letícia, Freiberger, Viviane, Dias, Paula, Horewicz, Verônica V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Age Aging Alzheimer's disease Animal cognition Animals Animals, Newborn - genetics Animals, Newborn - immunology Bacterial infections Behavior Blood-brain barrier Blood-Brain Barrier - immunology Brain Brain - growth & development Brain - immunology Cerebellar Cortex - immunology Cytokines Endotoxemia Endotoxemia - chemically induced Endotoxemia - immunology Glycogen Synthase Kinase 3 beta - genetics Gram-negative bacteria Hippocampus Hippocampus - immunology Humans IL-1β Immune response Immune system Immunological memory Impairment Infants (Newborn) Infections Inflammation Inflammation - chemically induced Inflammation - genetics Inflammation - immunology Instrument industry Kinases Laboratory animals Lipopolysaccharides Lipopolysaccharides - toxicity Membrane permeability Memory Memory tasks Mice Mitogens Mortality Neonates Neurodegenerative diseases Neurology Neurosciences Neurosurgery Permeability Proteins Psychiatry Risk factors Rodents Sepsis Spatial analysis Spatial memory Tau protein tau Proteins - genetics Tumor necrosis factor-α Visual cortex
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!