Podoplanin neutralization improves cardiac remodeling and function after myocardial infarction

Podoplanin (PDPN), a small mucin-type transmembrane glycoprotein, has been recently shown to be expressed by lymphangiogenic, fibrogenic, and mesenchymal progenitor cells in the acutely and chronically infarcted myocardium. PDPN binds to a C-type lectin–like receptor 2 highly expressed by CD11b hi c...

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Veröffentlicht in:	JCI insight 2019-08, Vol.4 (15)
Hauptverfasser:	Cimini, Maria, Garikipati, Venkata Naga Srikanth, de Lucia, Claudio, Cheng, Zhongjian, Wang, Chunlin, Truongcao, May M., Lucchese, Anna Maria, Roy, Rajika, Benedict, Cindy, Goukassian, David A., Koch, Walter J., Kishore, Raj
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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