Association Between Serum Neurofilament Light Chain Levels and Long-term Disease Course Among Patients With Multiple Sclerosis Followed up for 12 Years

IMPORTANCE: Blood sample–based biomarkers that are associated with clinically meaningful outcomes for patients with multiple sclerosis (MS) have not been developed. OBJECTIVE: To evaluate the potential of serum neurofilament light chain (sNFL) measurements as a biomarker of disease activity and prog...

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Veröffentlicht in:	Archives of neurology (Chicago) 2019-11, Vol.76 (11), p.1359-1366
Hauptverfasser:	Cantó, Ester, Barro, Christian, Zhao, Chao, Caillier, Stacy J, Michalak, Zuzanna, Bove, Riley, Tomic, Davorka, Santaniello, Adam, Häring, Dieter A, Hollenbach, Jill, Henry, Roland G, Cree, Bruce A. C, Kappos, Ludwig, Leppert, David, Hauser, Stephen L, Benkert, Pascal, Oksenberg, Jorge R, Kuhle, Jens
Format:	Artikel
Sprache:	eng
Schlagworte:	Atrophy Biomarkers Brain Chains Clinical decision making Clinical significance Datasets Decision making Evaluation Light levels Magnetic resonance imaging Medical imaging Multiple sclerosis Neuroimaging Online First Original Investigation Patients Proteomics Quality control Statistical analysis Statistical methods Variance
Online-Zugang:	Volltext
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