Extracellular vesicles mediate the horizontal transfer of an active LINE-1 retrotransposon

Long interspersed element-1 (LINE-1 or L1) retrotransposons replicate through a copy-and-paste mechanism using an RNA intermediate. However, little is known about the physical transmission of retrotransposon RNA between cells. To examine the horizontal transfer of an active human L1 retrotransposon...

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Veröffentlicht in:	Journal of extracellular vesicles 2019-12, Vol.8 (1), p.1643214-n/a
Hauptverfasser:	Kawamura, Yumi, Sanchez Calle, Anna, Yamamoto, Yusuke, Sato, Taka-Aki, Ochiya, Takahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics apolipoprotein Cancer Cells Centrifugation Exosomes Extracellular vesicles Gene expression Genomes Horizontal cells horizontal gene transfer Horizontal transfer Intermediates Long interspersed nucleotide elements Mutation Nanoparticles Plasmids Proteins Reporter gene Retrotransposition Ribonucleic acid RNA RNA transport Transmission electron microscopy transposable element
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