Highlight article: Long-term culture and characterization of patient-derived primary hepatocytes using conditional reprogramming

Cultivation of primary human hepatocytes (PHHs) often faces obstacles including failure of long-term in vitro culture, weak proliferation ability, rapid loss of liver-specific function and morphology, and tendency of fibrosis. Previous research focused on immortalization methods, such as telomerase...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 2019-08, Vol.244 (11), p.857-864
Hauptverfasser:	Su, Shan, Di Poto, Cristina, Roy, Rabindra, Liu, Xuefeng, Cui, Wanxing, Kroemer, Alexander, Ressom, Habtom W
Format:	Artikel
Sprache:	eng
Schlagworte:	Original Research
Online-Zugang:	Volltext
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