Candidalysin: discovery and function in Candida albicans infections

•Candidalysin is the first peptide toxin identified in any human fungal pathogen.•Candidalysin is critical for Candida albicans mucosal and systemic infections.•Candidalysin activates danger-response and damage-protection pathways in host cells.•Candidalysin activates the epidermal growth factor rec...

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Veröffentlicht in:	Current opinion in microbiology 2019-12, Vol.52, p.100-109
Hauptverfasser:	Naglik, Julian R, Gaffen, Sarah L, Hube, Bernhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Candida albicans - metabolism Candidiasis - microbiology Candidiasis - physiopathology Fungal Proteins - immunology Fungal Proteins - metabolism Host-Pathogen Interactions Humans Mycotoxins - immunology Mycotoxins - metabolism Virulence Factors - immunology Virulence Factors - metabolism
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