NMR Metabolomics Show Evidence for Mitochondrial Oxidative Stress in a Mouse Model of Polycystic Ovary Syndrome

Polycystic ovary syndrome (PCOS) is associated with metabolic and endocrine disorders in women of reproductive age. The etiology of PCOS is still unknown. Mice prenatally treated with glucocorticoids exhibit metabolic disturbances that are similar to those seen in women with PCOS. We used an untarge...

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Veröffentlicht in:Journal of proteome research 2015-08, Vol.14 (8), p.3284-3291
Hauptverfasser: Selen, Ebru Selin, Bolandnazar, Zeinab, Tonelli, Marco, Bütz, Daniel E, Haviland, Julia A, Porter, Warren P, Assadi-Porter, Fariba M
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Sprache:eng
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