Disordered Mechanical Stress and Tissue Engineering Therapies in Intervertebral Disc Degeneration

Low back pain (LBP), commonly induced by intervertebral disc degeneration, is a lumbar disease with worldwide prevalence. However, the mechanism of degeneration remains unclear. The intervertebral disc is a nonvascular organ consisting of three components: Nucleus pulposus, annulus fibrosus, and end...

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Veröffentlicht in:	Polymers 2019-07, Vol.11 (7), p.1151
Hauptverfasser:	Zhao, Runze, Liu, Wanqian, Xia, Tingting, Yang, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Annuli Apoptosis Binding sites Biochemistry Biomechanics Collagen Connective tissue Degeneration Degenerative disc disease External pressure Gene expression Growth factors Influence Intervertebral discs Kinases Literature reviews Pain Review Signs and symptoms Tissue engineering
Online-Zugang:	Volltext
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