Plasmonic Paper Microneedle Patch for On-Patch Detection of Molecules in Dermal Interstitial Fluid

Minimally invasive devices to detect molecules in dermal interstitial fluid (ISF) are desirable for point-of-care diagnostic and monitoring applications. In this study, we developed a microneedle (MN) patch that collects ISF for on-patch biomarker analysis by surface-enhanced Raman scattering (SERS)...

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Veröffentlicht in:	ACS sensors 2019-06, Vol.4 (6), p.1569-1576
Hauptverfasser:	Kolluru, Chandana, Gupta, Rohit, Jiang, Qisheng, Williams, Mikayla, Gholami Derami, Hamed, Cao, Sisi, Noel, Richard K, Singamaneni, Srikanth, Prausnitz, Mark R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dermis - chemistry Extracellular Fluid - chemistry Female Gold - chemistry Injections, Intradermal - instrumentation Injections, Intradermal - methods Nanotubes - chemistry Needles Point-of-Care Testing Polystyrenes - chemistry Proof of Concept Study Rats Rhodamines - analysis Rhodamines - blood Rhodamines - pharmacokinetics Spectrum Analysis, Raman - methods
Online-Zugang:	Volltext
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