Design of PD-L1 inhibitors for lung cancer

The progression of lung cancer is associated with inactivation of programmed cell death protein 1, abbreviated as PD- 1 which regulates the suppression of the body's immune system by suppressing T- cell inflammatory activity and is responsible for preventing cancer cell growth. It is of interes...

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Veröffentlicht in:	Bioinformation 2019, Vol.15 (2), p.139-150
Hauptverfasser:	Udhwani, Trishang, Mukherjee, Sourav, Sharma, Khushboo, Sweta, Jajoriya, Khandekar, Natasha, Nayarisseri, Anuraj, Singh, Sanjeev Kumar
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cancer Cell death Cytotoxicity Deactivation Immune system Inactivation Inflammation Inhibitors Intestinal absorption Intestine Lung cancer Molecular docking Molecular structure PD-1 protein PD-L1 protein Proteins Toxicity
Online-Zugang:	Volltext
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