Acquired resistance mechanisms to afatinib in HER2‐amplified gastric cancer cells

Cancer treatment, especially that for breast and lung cancer, has entered a new era and continues to evolve, with the development of genome analysis technology and the advent of molecular targeted drugs including tyrosine kinase inhibitors. Nevertheless, acquired drug resistance to molecular targete...

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Veröffentlicht in:Cancer science 2019-08, Vol.110 (8), p.2549-2557
Hauptverfasser: Yoshioka, Takahiro, Shien, Kazuhiko, Takeda, Tatsuaki, Takahashi, Yuta, Kurihara, Eisuke, Ogoshi, Yusuke, Namba, Kei, Torigoe, Hidejiro, Sato, Hiroki, Tomida, Shuta, Yamamoto, Hiromasa, Soh, Junichi, Fujiwara, Toshiyoshi, Toyooka, Shinichi
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Sprache:eng
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