Small lung tumor biopsy samples are feasible for high quality targeted next generation sequencing

Next‐generation sequencing (NGS) has been implemented in clinical oncology to analyze multiple genes and to guide therapy. In patients with advanced lung cancer, small biopsies such as computed tomography‐guided needle biopsy (CTNB), endobronchial ultrasound‐guided transbronchial needle aspiration (...

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Veröffentlicht in:	Cancer science 2019-08, Vol.110 (8), p.2652-2657
Hauptverfasser:	Kage, Hidenori, Kohsaka, Shinji, Shinozaki‐Ushiku, Aya, Hiraishi, Yoshihisa, Sato, Jiro, Nagayama, Kazuhiro, Ushiku, Tetsuo, Takai, Daiya, Nakajima, Jun, Miyagawa, Kiyoshi, Aburatani, Hiroyuki, Mano, Hiroyuki, Nagase, Takahide
Format:	Artikel
Sprache:	eng
Schlagworte:	Biopsy Biopsy - methods bronchoscopy Cancer therapies Computed tomography CT‐guided needle biopsy Deoxyribonucleic acid DNA DNA - genetics DNA probes High-Throughput Nucleotide Sequencing - methods Humans Invasiveness Lung cancer Lung Neoplasms - genetics Metastases Methods Mutation Next-generation sequencing Original Paraffin Quality control Ribonucleic acid RNA RNA - genetics targeted next generation sequencing Thoracic surgery Thorax Tumors Ultrasonic imaging Ultrasound Variance analysis
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