Two Brain Sites for Cannabinoid Reward

The recent findings that Delta9tetrahydrocannabinol (Delta9THC), the active agent in marijuana and hashish, (1) is self-administered intravenously, (2) potentiates the rewarding effects of electrical brain stimulation, and (3) can establish conditioned place preferences in laboratory animals, sugges...

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Veröffentlicht in:	The Journal of neuroscience 2006-05, Vol.26 (18), p.4901-4907
Hauptverfasser:	Zangen, Abraham, Solinas, Marcello, Ikemoto, Satoshi, Goldberg, Steven R, Wise, Roy A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Animals Behavior, Animal Cannabinoids - metabolism Cannabinoids - pharmacology Cannabis Conditioning, Operant - drug effects Conditioning, Operant - physiology Dronabinol - pharmacology Male Motor Activity - drug effects Nucleus Accumbens - drug effects Nucleus Accumbens - physiology Psychotropic Drugs - pharmacology Rats Rats, Sprague-Dawley Reward Self Stimulation - drug effects Self Stimulation - physiology Time Factors Ventral Tegmental Area - drug effects Ventral Tegmental Area - physiology
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