Chronic Unpredictable Stress Exacerbates Lipopolysaccharide-Induced Activation of Nuclear Factor-κB in the Frontal Cortex and Hippocampus via Glucocorticoid Secretion
Although the anti-inflammatory actions of glucocorticoids (GCs) are well established in the periphery, these stress hormones can increase inflammation under some circumstances in the brain. The transcription factor nuclear factor-κB (NF-κB), which is inhibited by GCs, regulates numerous genes centra...
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Veröffentlicht in: | The Journal of neuroscience 2006-04, Vol.26 (14), p.3813-3820 |
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Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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