Enhanced Hippocampal Long-Term Potentiation and Spatial Learning in Aged 11β-Hydroxysteroid Dehydrogenase Type 1 Knock-Out Mice

Glucocorticoids are pivotal in the maintenance of memory and cognitive functions as well as other essential physiological processes including energy metabolism, stress responses, and cell proliferation. Normal aging in both rodents and humans is often characterized by elevated glucocorticoid levels...

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Veröffentlicht in:The Journal of neuroscience 2007-09, Vol.27 (39), p.10487-10496
Hauptverfasser: Yau, Joyce L. W., McNair, Kara M., Noble, June, Brownstein, David, Hibberd, Carina, Morton, Nik, Mullins, John J., Morris, Richard G. M., Cobb, Stuart, Seckl, Jonathan R.
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Sprache:eng
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