NR2B Signaling Regulates the Development of Synaptic AMPA Receptor Current

The postnatal maturation of glutamatergic synapses involves a change in composition and functional contribution of postsynaptic receptors. Developing cortical synapses are dominated by NMDA receptors (NMDARs) containing NR2B subunits and are characterized by a low ratio of AMPA/NMDA receptor-mediate...

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Veröffentlicht in:	The Journal of neuroscience 2007-12, Vol.27 (49), p.13446-13456
Hauptverfasser:	Hall, Benjamin J, Ripley, Beth, Ghosh, Anirvan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured Female Gene Targeting Mice Mice, Knockout Pregnancy Rats Receptors, AMPA - metabolism Receptors, AMPA - physiology Receptors, N-Methyl-D-Aspartate - deficiency Receptors, N-Methyl-D-Aspartate - genetics Receptors, N-Methyl-D-Aspartate - physiology Signal Transduction - genetics Signal Transduction - physiology Synapses - physiology
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