Circ‐SERPINE2 promotes the development of gastric carcinoma by sponging miR‐375 and modulating YWHAZ

Objectives Circular RNAs (circRNAs) exist extensively in the eukaryotic genome. The study aimed to identify the role of hsa_circ_0008365 (Circ‐SERPINE2) in gastric carcinoma (GC) cells and its downstream mechanisms. Materials and methods Gene Expression Omnibus (GEO) database was applied to screen d...

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Veröffentlicht in:	Cell proliferation 2019-07, Vol.52 (4), p.e12648-n/a
Hauptverfasser:	Liu, Jianing, Song, Suzhen, Lin, Sen, Zhang, Mingbao, Du, Yating, Zhang, Dongdong, Xu, Weihua, Wang, Hongbo
Format:	Artikel
Sprache:	eng
Schlagworte:	14-3-3 Proteins - genetics 14‐3‐3 zeta Apoptosis Apoptosis - genetics Assaying Cell cycle Cell Cycle - genetics Cell Line, Tumor Cell proliferation Cell Proliferation - genetics circular RNA Disease Progression Down-Regulation - genetics Flow cytometry Gastric cancer gastric carcinoma Gene expression Gene Expression Regulation, Neoplastic - genetics Genomes Humans Immunohistochemistry MicroRNAs - genetics miRNA miR‐375 Original Ribonuclease Ribonucleic acid RNA RNA, Circular Serpin E2 - genetics Solid tumors Stomach Neoplasms - genetics Stomach Neoplasms - pathology Therapeutic applications Up-Regulation - genetics Websites YWHAZ
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