Early Deficits in Spatial Memory and Theta Rhythm in Experimental Temporal Lobe Epilepsy

Patients with temporal lobe epilepsy (TLE), the most common form of epilepsy in adults, often display cognitive deficits. The time course and underlying mechanisms of cognitive decline remain unknown during epileptogenesis (the process leading to epilepsy). Using the rat pilocarpine model of TLE, we...

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Veröffentlicht in:	The Journal of neuroscience 2009-04, Vol.29 (17), p.5402-5410
Hauptverfasser:	Chauviere, Laetitia, Rafrafi, Nadia, Thinus-Blanc, Catherine, Bartolomei, Fabrice, Esclapez, Monique, Bernard, Christophe
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cognitive science Epilepsy, Temporal Lobe - chemically induced Epilepsy, Temporal Lobe - physiopathology Male Memory - physiology Memory Disorders - chemically induced Memory Disorders - physiopathology Pilocarpine - toxicity Psychology Rats Rats, Wistar Spatial Behavior - drug effects Spatial Behavior - physiology Theta Rhythm - drug effects Time Factors
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