Aptamer-Functionalized Exosomes: Elucidating the Cellular Uptake Mechanism and the Potential for Cancer-Targeted Chemotherapy

Exosomes (Exos) are nanoscale natural vehicles for transporting biomolecules to facilitate cell-to-cell communication, indicating a high potential of them for delivering therapeutics/diagnostics. To improve their delivery capacity, a simple, noninvasive, and efficient strategy for functionalizing Ex...

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Veröffentlicht in:	Analytical chemistry (Washington) 2019-02, Vol.91 (3), p.2425-2430
Hauptverfasser:	Zou, Jianmei, Shi, Muling, Liu, Xiaojing, Jin, Cheng, Xing, Xiaojing, Qiu, Liping, Tan, Weihong
Format:	Artikel
Sprache:	eng
Schlagworte:	Aptamers Biomolecules Cancer cell communication Cell interactions Chemical compounds Chemistry Chemotherapy diagnostic techniques Drug delivery systems drug therapy drugs Exosomes Fluorescence fluorescent dyes Fluorophores Ligands neoplasm cells neoplasms oligonucleotides Precision medicine
Online-Zugang:	Volltext
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