Combining activatable nanodelivery with immunotherapy in a murine breast cancer model

A successful chemotherapy-immunotherapy solid-tumor protocol should accomplish the following goals: debulk large tumors, release tumor antigen for cross-presentation and cross-priming, release cancer-suppressive cytokines and enhance anti-tumor immune cell populations. Thermally-activated drug deliv...

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Veröffentlicht in:	Journal of controlled release 2019-06, Vol.303, p.42-54
Hauptverfasser:	Kheirolomoom, Azadeh, Silvestrini, Matthew T, Ingham, Elizabeth S, Mahakian, Lisa M, Tam, Sarah M, Tumbale, Spencer K, Foiret, Josquin, Hubbard, Neil E, Borowsky, Alexander D, Ferrara, Katherine W
Format:	Artikel
Sprache:	eng
Schlagworte:	adaptive immunity adjuvants agonists animal models antigens breast neoplasms cell death cell lines copper cytokines doxorubicin fever immunotherapy interferons intravenous injection mice neoplasm cells toxicity
Online-Zugang:	Volltext
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