Steady-State Activation and Modulation of the Concatemeric α1β2γ2L GABAA Receptor

The two-state coagonist model has been successfully used to analyze and predict peak current responses of the γ-aminobutyric acid type A (GABAA) receptor. The goal of the present study was to provide a model-based description of GABAA receptor activity under steady-state conditions after desensitiza...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular pharmacology 2019-09, Vol.96 (3), p.320-329
Hauptverfasser:	Germann, Allison L., Pierce, Spencer R., Burbridge, Ariel B., Steinbach, Joe Henry, Akk, Gustav
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!