Shear‐induced platelet aggregation increases in patients with proximal and severe coronary artery stenosis

Background: Shear stress generated in stenosed arteries promotes platelet thrombi formation at the stenosed sites by accelerating the binding of von Willebrand factor (vWF) to platelets. Shear‐induced platelet aggregation (SIPA) has been studied in acute coronary syndromes, but not in chronic corona...

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Veröffentlicht in:	Clinical cardiology (Mahwah, N.J.) N.J.), 2002-04, Vol.25 (4), p.154-160
Hauptverfasser:	Kawano, Koichi, Yoshino, Hideaki, Aoki, Nobuo, Udagawa, Hiroshi, Watanuki, Atsushi, Hioki, Yoshiko, Hasumura, Yukihisa, Yasumura, Toshikaki, Homori, Masashi, Murata, Mitsuru, Ikeda, Yasuo, Ishikawa, Kyozo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Analysis of Variance Angina Pectoris - blood Biological and medical sciences Cardiology. Vascular system Case-Control Studies Clinical Investigation Clinical Investigations Coronary Angiography coronary disease Coronary heart disease Coronary Stenosis - blood Coronary Stenosis - pathology Female Heart Hemorheology Humans Male Medical sciences Middle Aged Myocardial Infarction - blood platelet Platelet Aggregation - physiology stenosis Thrombosis - etiology von Willebrand factor von Willebrand Factor - analysis
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