Lumiflavin increases the sensitivity of ovarian cancer stem‐like cells to cisplatin by interfering with riboflavin

Here, we used lumiflavin, an inhibitor of riboflavin, as a new potential therapeutic chemosensitizer to ovarian cancer stem‐like cells (CSCs). This study demonstrates that the enrichment of riboflavin in CSCs is an important cause of its resistance to chemotherapy. Lumiflavin can effectively reduce...

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Veröffentlicht in:Journal of cellular and molecular medicine 2019-08, Vol.23 (8), p.5329-5339
Hauptverfasser: Yang, Ruhui, Wei, Zhe, Wu, Songquan
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Sprache:eng
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