Model to Calculate Harms and Benefits of Early vs Delayed Liver Transplantation for Patients With Alcohol-Associated Hepatitis

Early liver transplantation (without requiring a minimum period of sobriety) for severe alcohol-associated hepatitis (AH) is controversial: many centers delay eligibility until a specific period of sobriety (such as 6 months) has been achieved. To inform ongoing debate and policy, we modeled long-te...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2019-08, Vol.157 (2), p.472-480.e5
Hauptverfasser:	Lee, Brian P., Samur, Sumeyye, Dalgic, Ozden O., Bethea, Emily D., Lucey, Michael R., Weinberg, Ethan, Hsu, Christine, Rinella, Mary E., Im, Gene Y., Fix, Oren K., Therapondos, George, Han, Hyosun, Victor, David W., Voigt, Michael D., Eswaran, Sheila, Terrault, Norah A., Chhatwal, Jagpreet
Format:	Artikel
Sprache:	eng
Schlagworte:	6-month rule ACCELERATE-AH Adult Alcohol Abstinence Alcohol Drinking - adverse effects Alcohol Drinking - prevention & control drinking End Stage Liver Disease - diagnosis End Stage Liver Disease - etiology End Stage Liver Disease - mortality End Stage Liver Disease - surgery Female Hepatitis, Alcoholic - complications Hepatitis, Alcoholic - diagnosis Hepatitis, Alcoholic - mortality Hepatitis, Alcoholic - surgery Humans Life Expectancy Liver Transplantation - methods Liver Transplantation - standards Male Markov model Middle Aged Models, Biological Prospective Studies Risk Assessment - methods Severity of Illness Index Survival Analysis Time Factors Time-to-Treatment Treatment Outcome Waiting Lists
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