Impact of Systolic Dysfunction in Genotyped Hypertrophic Cardiomyopathy

Background: Hypertrophic cardiomyopathy (HCM) is a disease of the sarcomere, and approximately 5% of cases of HCM show systolic dysfunction with poor prognosis. Few data exist regarding the systolic dysfunction in a large population of genotyped HCM subjects. Hypothesis: The aim of this study was to...

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Veröffentlicht in:	Clinical cardiology (Mahwah, N.J.) N.J.), 2013-03, Vol.36 (3), p.160-165
Hauptverfasser:	Fujino, Noboru, Konno, Tetsuo, Hayashi, Kenshi, Hodatsu, Akihiko, Fujita, Takashi, Tsuda, Toyonobu, Nagata, Yoji, Kawashiri, Masa‐aki, Ino, Hidekazu, Yamagishi, Masakazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Cardiomyopathy, Hypertrophic - complications Cardiomyopathy, Hypertrophic - diagnostic imaging Cardiomyopathy, Hypertrophic - genetics Cardiomyopathy, Hypertrophic - physiopathology Carrier Proteins - genetics Chi-Square Distribution Clinical Investigation Clinical Investigations Female Genetic Predisposition to Disease Humans Kaplan-Meier Estimate Longitudinal Studies Male Middle Aged Multivariate Analysis Mutation Phenotype Prognosis Proportional Hazards Models Risk Assessment Risk Factors Stroke Volume - genetics Systole - genetics Time Factors Ultrasonography Ventricular Dysfunction, Left - diagnostic imaging Ventricular Dysfunction, Left - genetics Ventricular Dysfunction, Left - physiopathology Ventricular Function, Left - genetics Ventricular Pressure - genetics
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