Fluidic Force Microscopy Demonstrates That Homophilic Adhesion by Candida albicans Als Proteins Is Mediated by Amyloid Bonds between Cells

The fungal pathogen Candida albicans frequently forms drug-resistant biofilms in hospital settings and in chronic disease patients. Cell adhesion and biofilm formation involve a family of cell surface Als (agglutinin-like sequence) proteins. It is now well documented that amyloid-like clusters of la...

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Veröffentlicht in:	Nano letters 2019-06, Vol.19 (6), p.3846-3853
Hauptverfasser:	Dehullu, Jérôme, Valotteau, Claire, Herman-Bausier, Philippe, Garcia-Sherman, Melissa, Mittelviefhaus, Maximilian, Vorholt, Julia A, Lipke, Peter N, Dufrêne, Yves F
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid - metabolism Biofilms Candida albicans - cytology Candida albicans - physiology Candidiasis - microbiology Cell Adhesion Cell Adhesion Molecules - metabolism Equipment Design Fungal Proteins - metabolism Humans Microscopy, Atomic Force - instrumentation Single-Cell Analysis
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