Survival analysis of intraoperative blood salvage for patients with malignancy disease: A PRISMA-compliant systematic review and meta-analysis
Intraoperative blood salvage as a blood-saving strategy has been widely used in surgery. Considering its theoretic risk of malignant tumor cells being reinfused and the corresponding blood metastases, the safety of intraoperative blood salvage in cancer surgery remains controversial. Following the P...
Gespeichert in:
| Veröffentlicht in: | Medicine (Baltimore) 2019-07, Vol.98 (27), p.e16040-e16040 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e16040 |
|---|---|
| container_issue | 27 |
| container_start_page | e16040 |
| container_title | Medicine (Baltimore) |
| container_volume | 98 |
| creator | Wu, Wei-Wei Zhang, Wei-Yi Zhang, Wei-Han Yang, Lei Deng, Xiao-Qian Ou, Meng-Chan Yang, Yao-Xin Liu, Hai-Bei Zhu, Tao |
| description | Intraoperative blood salvage as a blood-saving strategy has been widely used in surgery. Considering its theoretic risk of malignant tumor cells being reinfused and the corresponding blood metastases, the safety of intraoperative blood salvage in cancer surgery remains controversial.
Following the Preferred Reporting Items for Systemic Review and Meta-Analysis (PRISMA), we searched the Cochrane Library, MEDLINE and EMBASE to November 2017. We included only studies comparing intraoperative blood salvage with allogeneic blood transfusion.
This meta-analysis included 9 studies with 4354 patients with 1346 patients in the intraoperative blood salvage group and 3008 patients in the allogeneic blood transfusion group. There were no significant differences in the 5-year overall survival outcome (odds ratio [OR] 1.12; 95% confidence interval [CI], 0.80-1.58), 5-year disease-free survival outcome (OR 1.08; 95% CI 0.86-1.35), or 5-year recurrence rate (OR 0.86; 95% CI 0.71-1.05) between the 2 study groups. Subgroup analysis also showed no significant differences in the 5-year overall survival outcome (OR 0.97; 95% CI 0.57-1.67) of hepatocellular carcinoma patients in liver transplantation.
For patients with malignant disease, intraoperative blood salvage did not increase the tumor recurrence rate and had comparable survival outcomes with allogeneic blood transfusion. |
| doi_str_mv | 10.1097/MD.0000000000016040 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6635293</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2253288037</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3552-aa89336fa1bed614ba41efa520aad430c7c9b7059da2f78e5805f8f8e1511bc43</originalsourceid><addsrcrecordid>eNpdkUuP0zAUhS0EYkrhFyAhL9lk8COOExZI1QyPkaYCMbC2bpyb1uDExU5S9U_wm0npzPDwxov7nXOufQh5ztk5Z5V-tb48Z38OL1jOHpAFV7LIVFXkD8mCMaEyXen8jDxJ6dsMSS3yx-RMcqH17LEgP2_GOLkJPIUe_CG5RENLXT9ECDuMMLgJae1DaGgCP8EGaRsi3c0D7IdE927Y0g682_TQ2wNtXEJI-Jqu6KfPVzfrVWZDt_MO-oGmQxqwm5WWRpwc7ufMhnY4QHYX_pQ8asEnfHZ7L8nXd2-_XHzIrj--v7pYXWdWKiUygLKSsmiB19gUPK8h59iCEgygySWz2la1ZqpqQLS6RFUy1ZZtiVxxXttcLsmbk-9urDtsLB4f7M0uug7iwQRw5t9J77ZmEyZTFFKJOXtJXt4axPBjxDSYziWL3kOPYUxGCCVFWTKpZ1SeUBtDShHb-xjOzLFJs740_zc5q178veG95q66GchPwD74AWP67sc9RrNF8MP2t5_SlcgE4xWbv4JlR2shfwHNMK0f</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2253288037</pqid></control><display><type>article</type><title>Survival analysis of intraoperative blood salvage for patients with malignancy disease: A PRISMA-compliant systematic review and meta-analysis</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Wolters Kluwer Open Health</source><source>IngentaConnect Free/Open Access Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Wu, Wei-Wei ; Zhang, Wei-Yi ; Zhang, Wei-Han ; Yang, Lei ; Deng, Xiao-Qian ; Ou, Meng-Chan ; Yang, Yao-Xin ; Liu, Hai-Bei ; Zhu, Tao</creator><creatorcontrib>Wu, Wei-Wei ; Zhang, Wei-Yi ; Zhang, Wei-Han ; Yang, Lei ; Deng, Xiao-Qian ; Ou, Meng-Chan ; Yang, Yao-Xin ; Liu, Hai-Bei ; Zhu, Tao</creatorcontrib><description>Intraoperative blood salvage as a blood-saving strategy has been widely used in surgery. Considering its theoretic risk of malignant tumor cells being reinfused and the corresponding blood metastases, the safety of intraoperative blood salvage in cancer surgery remains controversial.
Following the Preferred Reporting Items for Systemic Review and Meta-Analysis (PRISMA), we searched the Cochrane Library, MEDLINE and EMBASE to November 2017. We included only studies comparing intraoperative blood salvage with allogeneic blood transfusion.
This meta-analysis included 9 studies with 4354 patients with 1346 patients in the intraoperative blood salvage group and 3008 patients in the allogeneic blood transfusion group. There were no significant differences in the 5-year overall survival outcome (odds ratio [OR] 1.12; 95% confidence interval [CI], 0.80-1.58), 5-year disease-free survival outcome (OR 1.08; 95% CI 0.86-1.35), or 5-year recurrence rate (OR 0.86; 95% CI 0.71-1.05) between the 2 study groups. Subgroup analysis also showed no significant differences in the 5-year overall survival outcome (OR 0.97; 95% CI 0.57-1.67) of hepatocellular carcinoma patients in liver transplantation.
For patients with malignant disease, intraoperative blood salvage did not increase the tumor recurrence rate and had comparable survival outcomes with allogeneic blood transfusion.</description><identifier>ISSN: 0025-7974</identifier><identifier>EISSN: 1536-5964</identifier><identifier>DOI: 10.1097/MD.0000000000016040</identifier><identifier>PMID: 31277097</identifier><language>eng</language><publisher>United States: the Author(s). Published by Wolters Kluwer Health, Inc</publisher><subject>Blood Transfusion, Autologous - adverse effects ; Disease-Free Survival ; Female ; Humans ; Male ; Neoplasm Recurrence, Local - etiology ; Neoplasms - surgery ; Operative Blood Salvage - adverse effects ; Retrospective Studies ; Survival Analysis ; Systematic Review and Meta-Analysis</subject><ispartof>Medicine (Baltimore), 2019-07, Vol.98 (27), p.e16040-e16040</ispartof><rights>the Author(s). Published by Wolters Kluwer Health, Inc.</rights><rights>Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3552-aa89336fa1bed614ba41efa520aad430c7c9b7059da2f78e5805f8f8e1511bc43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635293/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635293/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31277097$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wu, Wei-Wei</creatorcontrib><creatorcontrib>Zhang, Wei-Yi</creatorcontrib><creatorcontrib>Zhang, Wei-Han</creatorcontrib><creatorcontrib>Yang, Lei</creatorcontrib><creatorcontrib>Deng, Xiao-Qian</creatorcontrib><creatorcontrib>Ou, Meng-Chan</creatorcontrib><creatorcontrib>Yang, Yao-Xin</creatorcontrib><creatorcontrib>Liu, Hai-Bei</creatorcontrib><creatorcontrib>Zhu, Tao</creatorcontrib><title>Survival analysis of intraoperative blood salvage for patients with malignancy disease: A PRISMA-compliant systematic review and meta-analysis</title><title>Medicine (Baltimore)</title><addtitle>Medicine (Baltimore)</addtitle><description>Intraoperative blood salvage as a blood-saving strategy has been widely used in surgery. Considering its theoretic risk of malignant tumor cells being reinfused and the corresponding blood metastases, the safety of intraoperative blood salvage in cancer surgery remains controversial.
Following the Preferred Reporting Items for Systemic Review and Meta-Analysis (PRISMA), we searched the Cochrane Library, MEDLINE and EMBASE to November 2017. We included only studies comparing intraoperative blood salvage with allogeneic blood transfusion.
This meta-analysis included 9 studies with 4354 patients with 1346 patients in the intraoperative blood salvage group and 3008 patients in the allogeneic blood transfusion group. There were no significant differences in the 5-year overall survival outcome (odds ratio [OR] 1.12; 95% confidence interval [CI], 0.80-1.58), 5-year disease-free survival outcome (OR 1.08; 95% CI 0.86-1.35), or 5-year recurrence rate (OR 0.86; 95% CI 0.71-1.05) between the 2 study groups. Subgroup analysis also showed no significant differences in the 5-year overall survival outcome (OR 0.97; 95% CI 0.57-1.67) of hepatocellular carcinoma patients in liver transplantation.
For patients with malignant disease, intraoperative blood salvage did not increase the tumor recurrence rate and had comparable survival outcomes with allogeneic blood transfusion.</description><subject>Blood Transfusion, Autologous - adverse effects</subject><subject>Disease-Free Survival</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Neoplasm Recurrence, Local - etiology</subject><subject>Neoplasms - surgery</subject><subject>Operative Blood Salvage - adverse effects</subject><subject>Retrospective Studies</subject><subject>Survival Analysis</subject><subject>Systematic Review and Meta-Analysis</subject><issn>0025-7974</issn><issn>1536-5964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkUuP0zAUhS0EYkrhFyAhL9lk8COOExZI1QyPkaYCMbC2bpyb1uDExU5S9U_wm0npzPDwxov7nXOufQh5ztk5Z5V-tb48Z38OL1jOHpAFV7LIVFXkD8mCMaEyXen8jDxJ6dsMSS3yx-RMcqH17LEgP2_GOLkJPIUe_CG5RENLXT9ECDuMMLgJae1DaGgCP8EGaRsi3c0D7IdE927Y0g682_TQ2wNtXEJI-Jqu6KfPVzfrVWZDt_MO-oGmQxqwm5WWRpwc7ufMhnY4QHYX_pQ8asEnfHZ7L8nXd2-_XHzIrj--v7pYXWdWKiUygLKSsmiB19gUPK8h59iCEgygySWz2la1ZqpqQLS6RFUy1ZZtiVxxXttcLsmbk-9urDtsLB4f7M0uug7iwQRw5t9J77ZmEyZTFFKJOXtJXt4axPBjxDSYziWL3kOPYUxGCCVFWTKpZ1SeUBtDShHb-xjOzLFJs740_zc5q178veG95q66GchPwD74AWP67sc9RrNF8MP2t5_SlcgE4xWbv4JlR2shfwHNMK0f</recordid><startdate>20190701</startdate><enddate>20190701</enddate><creator>Wu, Wei-Wei</creator><creator>Zhang, Wei-Yi</creator><creator>Zhang, Wei-Han</creator><creator>Yang, Lei</creator><creator>Deng, Xiao-Qian</creator><creator>Ou, Meng-Chan</creator><creator>Yang, Yao-Xin</creator><creator>Liu, Hai-Bei</creator><creator>Zhu, Tao</creator><general>the Author(s). Published by Wolters Kluwer Health, Inc</general><general>Wolters Kluwer Health</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20190701</creationdate><title>Survival analysis of intraoperative blood salvage for patients with malignancy disease: A PRISMA-compliant systematic review and meta-analysis</title><author>Wu, Wei-Wei ; Zhang, Wei-Yi ; Zhang, Wei-Han ; Yang, Lei ; Deng, Xiao-Qian ; Ou, Meng-Chan ; Yang, Yao-Xin ; Liu, Hai-Bei ; Zhu, Tao</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3552-aa89336fa1bed614ba41efa520aad430c7c9b7059da2f78e5805f8f8e1511bc43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Blood Transfusion, Autologous - adverse effects</topic><topic>Disease-Free Survival</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Neoplasm Recurrence, Local - etiology</topic><topic>Neoplasms - surgery</topic><topic>Operative Blood Salvage - adverse effects</topic><topic>Retrospective Studies</topic><topic>Survival Analysis</topic><topic>Systematic Review and Meta-Analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wu, Wei-Wei</creatorcontrib><creatorcontrib>Zhang, Wei-Yi</creatorcontrib><creatorcontrib>Zhang, Wei-Han</creatorcontrib><creatorcontrib>Yang, Lei</creatorcontrib><creatorcontrib>Deng, Xiao-Qian</creatorcontrib><creatorcontrib>Ou, Meng-Chan</creatorcontrib><creatorcontrib>Yang, Yao-Xin</creatorcontrib><creatorcontrib>Liu, Hai-Bei</creatorcontrib><creatorcontrib>Zhu, Tao</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicine (Baltimore)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wu, Wei-Wei</au><au>Zhang, Wei-Yi</au><au>Zhang, Wei-Han</au><au>Yang, Lei</au><au>Deng, Xiao-Qian</au><au>Ou, Meng-Chan</au><au>Yang, Yao-Xin</au><au>Liu, Hai-Bei</au><au>Zhu, Tao</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Survival analysis of intraoperative blood salvage for patients with malignancy disease: A PRISMA-compliant systematic review and meta-analysis</atitle><jtitle>Medicine (Baltimore)</jtitle><addtitle>Medicine (Baltimore)</addtitle><date>2019-07-01</date><risdate>2019</risdate><volume>98</volume><issue>27</issue><spage>e16040</spage><epage>e16040</epage><pages>e16040-e16040</pages><issn>0025-7974</issn><eissn>1536-5964</eissn><abstract>Intraoperative blood salvage as a blood-saving strategy has been widely used in surgery. Considering its theoretic risk of malignant tumor cells being reinfused and the corresponding blood metastases, the safety of intraoperative blood salvage in cancer surgery remains controversial.
Following the Preferred Reporting Items for Systemic Review and Meta-Analysis (PRISMA), we searched the Cochrane Library, MEDLINE and EMBASE to November 2017. We included only studies comparing intraoperative blood salvage with allogeneic blood transfusion.
This meta-analysis included 9 studies with 4354 patients with 1346 patients in the intraoperative blood salvage group and 3008 patients in the allogeneic blood transfusion group. There were no significant differences in the 5-year overall survival outcome (odds ratio [OR] 1.12; 95% confidence interval [CI], 0.80-1.58), 5-year disease-free survival outcome (OR 1.08; 95% CI 0.86-1.35), or 5-year recurrence rate (OR 0.86; 95% CI 0.71-1.05) between the 2 study groups. Subgroup analysis also showed no significant differences in the 5-year overall survival outcome (OR 0.97; 95% CI 0.57-1.67) of hepatocellular carcinoma patients in liver transplantation.
For patients with malignant disease, intraoperative blood salvage did not increase the tumor recurrence rate and had comparable survival outcomes with allogeneic blood transfusion.</abstract><cop>United States</cop><pub>the Author(s). Published by Wolters Kluwer Health, Inc</pub><pmid>31277097</pmid><doi>10.1097/MD.0000000000016040</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0025-7974 |
| ispartof | Medicine (Baltimore), 2019-07, Vol.98 (27), p.e16040-e16040 |
| issn | 0025-7974 1536-5964 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6635293 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Wolters Kluwer Open Health; IngentaConnect Free/Open Access Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Blood Transfusion, Autologous - adverse effects Disease-Free Survival Female Humans Male Neoplasm Recurrence, Local - etiology Neoplasms - surgery Operative Blood Salvage - adverse effects Retrospective Studies Survival Analysis Systematic Review and Meta-Analysis |
| title | Survival analysis of intraoperative blood salvage for patients with malignancy disease: A PRISMA-compliant systematic review and meta-analysis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T20%3A58%3A54IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Survival%20analysis%20of%20intraoperative%20blood%20salvage%20for%20patients%20with%20malignancy%20disease:%20A%20PRISMA-compliant%20systematic%20review%20and%20meta-analysis&rft.jtitle=Medicine%20(Baltimore)&rft.au=Wu,%20Wei-Wei&rft.date=2019-07-01&rft.volume=98&rft.issue=27&rft.spage=e16040&rft.epage=e16040&rft.pages=e16040-e16040&rft.issn=0025-7974&rft.eissn=1536-5964&rft_id=info:doi/10.1097/MD.0000000000016040&rft_dat=%3Cproquest_pubme%3E2253288037%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2253288037&rft_id=info:pmid/31277097&rfr_iscdi=true |