Dicer prevents genome instability in response to replication stress

Dicer, an endoribonuclease best-known for its role in microRNA biogenesis and RNA interference pathway, has been shown to play a role in the DNA damage response and repair of double-stranded DNA breaks (DSBs) in mammalian cells. However, it remains unknown whether Dicer is also important to preserve...

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Veröffentlicht in:Oncotarget 2019-07, Vol.10 (43), p.4407-4423
Hauptverfasser: Fragkos, Michalis, Barra, Viviana, Egger, Tom, Bordignon, Benoit, Lemacon, Delphine, Naim, Valeria, Coquelle, Arnaud
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Sprache:eng
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