Early life stress enhances behavioral vulnerability to stress through the activation of REST4-mediated gene transcription in the medial prefrontal cortex of rodents

There is growing evidence suggesting that early life events have long-term effects on the neuroendocrine and behavioral developments of rodents. However, little is known about the involvement of early life events in the susceptibility to subsequent stress exposure during adulthood. The present study...

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Veröffentlicht in:The Journal of neuroscience 2010-11, Vol.30 (45), p.15007-15018
Hauptverfasser: Uchida, Shusaku, Hara, Kumiko, Kobayashi, Ayumi, Funato, Hiromasa, Hobara, Teruyuki, Otsuki, Koji, Yamagata, Hirotaka, McEwen, Bruce S, Watanabe, Yoshifumi
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Sprache:eng
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